Molecular structure of Adenosine 3′-phosphate 5′-phosphosulfate lithium salt, CAS Number: 109434-21-1
Adenosine 3′-phosphate 5′-phosphosulfate lithium salt (CAS 109434-21-1)
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Alternate Names:
Adenosine 3′-phosphate 5′-phosphosulfate lithium salt also known as 3′-Phosphoadenosine 5′-phosphosulfate lithium salt; APPS; Active sulfate; PAPS; 3′-Phosphoadenosine-5′-phosphosulfate Lithium Salt Hydrate
Application:
Adenosine 3′-phosphate 5′-phosphosulfate lithium salt is a commonly used sulfonate donor for sulfonation of glycans
CAS Number:
109434-21-1
Purity:
≥60%
Molecular Weight:
507.26
Molecular Formula:
C10H15N5O13P2S•xLi
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Adenosine 3′-phosphate 5′-phosphosulfate lithium salt is frequently used in biochemical research, particularly in the study of sulfation reactions, where it serves as a sulfate donor. In enzymology, it is often utilized to investigate sulfotransferase enzymes, which are key in the metabolism of various biomolecules. Researchers also employ this compound in the exploration of protein and peptide modifications, where sulfation plays a role in altering the function and activity of these biomolecules. Additionally, it is used in the field of molecular biology to examine gene expression regulation, since sulfate groups can influence the binding of transcription factors to DNA. The compound′s role in biological sulfation pathways makes it valuable for studies into the mechanisms of cellular signaling and metabolic regulation.
Adenosine 3′-phosphate 5′-phosphosulfate lithium salt (CAS 109434-21-1) References
- Metabolism of a highly selective gelatinase inhibitor generates active metabolite. | Lee, M., et al. 2007. Chem Biol Drug Des. 70: 371-82. PMID: 17927722
- Studies on bovine adrenal estrogen sulfotransferase. III. Facile synthesis of 3'-phospho- and 2'-phosphoadenosine 5'-phosphosulfate. | Horwitz, JP., et al. 1977. Biochim Biophys Acta. 480: 376-81. PMID: 189816
- Reduced GPIIb/IIIa expression in platelets hyposensitive to catecholamines when activated with TRAP. | Kim, JM., et al. 2009. Thromb Res. 124: 90-5. PMID: 19232685
- Expression of heparan sulfate sulfotransferases in Kluyveromyces lactis and preparation of 3'-phosphoadenosine-5'-phosphosulfate. | Zhou, X., et al. 2011. Glycobiology. 21: 771-80. PMID: 21224284
- Sulfate in fetal development. | Dawson, PA. 2011. Semin Cell Dev Biol. 22: 653-9. PMID: 21419855
- Sulfation of selected mono-hydroxyflavones by sulfotransferases in vitro: a species and gender comparison. | Yang, CH., et al. 2011. J Pharm Pharmacol. 63: 967-70. PMID: 21635263
- Investigation on the enantioselectivity of the sulfation of the methylenedioxymethamphetamine metabolites 3,4-dihydroxymethamphetamine and 4-hydroxy-3-methoxymethamphetamine using the substrate-depletion approach. | Schwaninger, AE., et al. 2011. Drug Metab Dispos. 39: 1998-2002. PMID: 21795466
- Golgi-resident PAP-specific 3'-phosphatase-coupled sulfotransferase assays. | Prather, B., et al. 2012. Anal Biochem. 423: 86-92. PMID: 22289690
- Metabolism studies of ifenprodil, a potent GluN2B receptor antagonist. | Falck, E., et al. 2014. J Pharm Biomed Anal. 88: 96-105. PMID: 24042122
- In vitro and in vivo biotransformation of WMS-1410, a potent GluN2B selective NMDA receptor antagonist. | Falck, E., et al. 2014. J Pharm Biomed Anal. 94: 36-44. PMID: 24534302
- Favipiravir inhibits acetaminophen sulfate formation but minimally affects systemic pharmacokinetics of acetaminophen. | Zhao, Y., et al. 2015. Br J Clin Pharmacol. 80: 1076-85. PMID: 25808818
- Identification of a major radiometabolite of [11C]PBB3. | Hashimoto, H., et al. 2015. Nucl Med Biol. 42: 905-10. PMID: 26420569
- Metabolic studies of selective androgen receptor modulators RAD140 and S-23 in horses. | So, YM., et al. 2021. Drug Test Anal. 13: 318-337. PMID: 32853476
- Comprehensive metabolic study of IOX4 in equine urine and plasma using liquid chromatography/electrospray ionization Q Exactive high-resolution mass spectrometer for the purpose of doping control. | Ishii, H., et al. 2022. Drug Test Anal. 14: 233-251. PMID: 34612014
- Investigation of the factors responsible for the low oral bioavailability of alizarin using a sensitive LC-MS/MS method: In vitro, in situ, and in vivo evaluations. | Seo, SW., et al. 2023. Drug Dev Res.. PMID: 36811607
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Adenosine 3′-phosphate 5′-phosphosulfate lithium salt, 1 mg | sc-210759 | 1 mg | $210.00 | |||
Adenosine 3′-phosphate 5′-phosphosulfate lithium salt, 5 mg | sc-210759A | 5 mg | $755.00 | |||
Adenosine 3′-phosphate 5′-phosphosulfate lithium salt, 25 mg | sc-210759C | 25 mg | $2800.00 |