Molecular structure of Adenosine 3′,5′-cyclic monophosphate tris salt, CAS Number: 102029-77-6
Adenosine 3′,5′-cyclic monophosphate tris salt (CAS 102029-77-6)
Alternate Names:
cyclic AMP
Application:
Adenosine 3′,5′-cyclic monophosphate tris salt is a messenger used for intracellular signal transduction
CAS Number:
102029-77-6
Purity:
≥97%
Molecular Weight:
450.34
Molecular Formula:
C10H12N5O6P•C4H11NO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Adenosine 3′,5′-cyclic monophosphate tris salt is a naturally-occurring activator of acyclic-AMP-dependent protein kinase (PKA). cAMP is an important second messenger that is linked in many systems to neurotransmitter- or hormone-induced receptor stimulation. The cAMP/PKA signaling pathway shows to inhibit cell proliferation, induce differentiation and lead to apoptosis.
Adenosine 3′,5′-cyclic monophosphate tris salt (CAS 102029-77-6) References
- 6-OHDA-induced hemiparkinsonism and chronic L-DOPA treatment increase dopamine D1-stimulated [(3)H]-GABA release and [(3)H]-cAMP production in substantia nigra pars reticulata of the rat. | Rangel-Barajas, C., et al. 2008. Neuropharmacology. 55: 704-11. PMID: 18588904
- L-DOPA-induced dyskinesia in hemiparkinsonian rats is associated with up-regulation of adenylyl cyclase type V/VI and increased GABA release in the substantia nigra reticulata. | Rangel-Barajas, C., et al. 2011. Neurobiol Dis. 41: 51-61. PMID: 20736067
- Modulation of the inhibitory action of ATP on acetylcholine-activated current by protein phosphorylation in rat sympathetic neurons. | Nakazawa, K. 1994. Pflugers Arch. 427: 129-35. PMID: 8058461
- Cyclic AMP and calcium in the transduction of hypothalamic neurohormone action in human pituitary tumors. | Spada, A., et al. 1997. Horm Res. 47: 235-9. PMID: 9167957
- Up-regulation of the cAMP/PKA pathway inhibits proliferation, induces differentiation, and leads to apoptosis in malignant gliomas. | Chen, TC., et al. 1998. Lab Invest. 78: 165-74. PMID: 9484714
- Cyclic AMP signaling and gene regulation. | Daniel, PB., et al. 1998. Annu Rev Nutr. 18: 353-83. PMID: 9706229
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Adenosine 3',5'-cyclic monophosphate tris salt, 500 mg | sc-214498 | 500 mg | $389.00 |