Molecular structure of Adenosine 3′,5′-cyclic monophosphate sodium salt monohydrate, CAS Number: 37839-81-9
Adenosine 3′,5′-cyclic monophosphate sodium salt monohydrate (CAS 37839-81-9)
Alternate Names:
cAMP-Na; Cyclic AMP Sodium Salt
Application:
Adenosine 3′,5′-cyclic monophosphate sodium salt monohydrate is a PKA (protein kinase A) activator
CAS Number:
37839-81-9
Purity:
≥98%
Molecular Weight:
369.20
Molecular Formula:
C10H11N5NaO6P•H2O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Adenosine 3′,5′-cyclic monophosphate sodium salt monohydrate is a naturally-occurring activator of PKA (cAMP-dependent protein kinase A). Cyclic-AMP is an important second messenger that is linked in many systems to neurotransmitter- or hormone-induced receptor stimulation. The cAMP/PKA signaling pathway has shown to induce differentiation, inhibit cell proliferation, and lead to apoptosis. Adenosine 3′,5′-cyclic monophosphate sodium salt monohydrate is an activator of Epac.
Adenosine 3′,5′-cyclic monophosphate sodium salt monohydrate (CAS 37839-81-9) References
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- Mapping ligand interactions with the hyperpolarization activated cyclic nucleotide modulated (HCN) ion channel binding domain using a soluble construct. | Scott, SP., et al. 2007. Biochemistry. 46: 9417-31. PMID: 17655202
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- Analysis of cell growth and gene expression of porcine adipose tissue-derived mesenchymal stem cells as nuclear donor cell. | Oh, HJ., et al. 2014. Dev Growth Differ. 56: 595-604. PMID: 25312433
- A highly sensitive electrochemiluminescence assay for protein kinase based on double-quenching of graphene quantum dots by G-quadruplex-hemin and gold nanoparticles. | Liu, J., et al. 2015. Biosens Bioelectron. 70: 54-60. PMID: 25794958
- Cell-free Protein Expression Using the Rapidly Growing Bacterium Vibrio natriegens. | Wiegand, DJ., et al. 2019. J Vis Exp.. PMID: 30933074
- Cyclic AMP and calcium in the transduction of hypothalamic neurohormone action in human pituitary tumors. | Spada, A., et al. 1997. Horm Res. 47: 235-9. PMID: 9167957
- Up-regulation of the cAMP/PKA pathway inhibits proliferation, induces differentiation, and leads to apoptosis in malignant gliomas. | Chen, TC., et al. 1998. Lab Invest. 78: 165-74. PMID: 9484714
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Activator of:
CA XV, Epac, and PKA.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Adenosine 3′,5′-cyclic monophosphate sodium salt monohydrate, 25 mg | sc-291840 | 25 mg | $56.00 | |||
Adenosine 3′,5′-cyclic monophosphate sodium salt monohydrate, 100 mg | sc-291840A | 100 mg | $92.00 | |||
Adenosine 3′,5′-cyclic monophosphate sodium salt monohydrate, 500 mg | sc-291840B | 500 mg | $270.00 | |||
Adenosine 3′,5′-cyclic monophosphate sodium salt monohydrate, 1 g | sc-291840C | 1 g | $398.00 |