Adenosine 2′,5′-diphosphate sodium salt (CAS 154146-84-6)
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Adenosine 2′,5′-diphosphate sodium salt is a nucleotide derivative that is utilized in biochemical and molecular biology research. This compound is of particular interest due to its structural similarity to adenosine 5′-triphosphate (ATP) and adenosine diphosphate (ADP), which are key molecules in energy transfer and signaling within cells. Researchers use Adenosine 2′,5′-diphosphate sodium salt to study enzyme kinetics and mechanisms, especially those of kinases and ATPases, as it can act as an inhibitor or a substrate analog in these reactions. It is also employed in investigations of nucleotide signaling pathways and the regulation of enzymatic activity. Furthermore, this compound is used in the development of biochemical assays for the screening of enzyme inhibitors, contributing to a better understanding of enzyme function and regulation.
Adenosine 2′,5′-diphosphate sodium salt (CAS 154146-84-6) References
- Crystal structures of the complexes of trichosanthin with four substrate analogs and catalytic mechanism of RNA N-glycosidase. | Gu, YJ. and Xia, ZX. 2000. Proteins. 39: 37-46. PMID: 10737925
- Mapping the ribonucleolytic active site of eosinophil-derived neurotoxin (EDN). High resolution crystal structures of EDN complexes with adenylic nucleotide inhibitors. | Leonidas, DD., et al. 2001. J Biol Chem. 276: 15009-17. PMID: 11154698
- P2y1 and P2y2 receptor-operated Ca2+ signals in primary cultures of cardiac microvascular endothelial cells. | Moccia, F., et al. 2001. Microvasc Res. 61: 240-52. PMID: 11336535
- The P2Y1 receptor antagonist adenosine-2',5'-diphosphate non-selectively antagonizes the platelet P2X1 ion channel. | Toth-Zsamboki, E., et al. 2001. Thromb Haemost. 86: 1338-9. PMID: 11816730
- A note on the structure of tri-phosphopyridine nucleotide. | HEPPEL, LA., et al. 1955. Biochem J. 60: 19-21. PMID: 14363177
- Unexpected binding mode for 2'-phosphoadenosine-based nucleotide inhibitors in complex with human angiogenin revealed by heteronuclear NMR spectroscopy. | Tonan, K., et al. 2003. Biochemistry. 42: 11137-49. PMID: 14503864
- Isolation and identification of two isomeric forms of malonyl-coenzyme A in commercial malonyl-coenzyme A. | Minkler, PE., et al. 2004. Anal Biochem. 328: 203-9. PMID: 15113698
- Crystal structure of a soluble form of human CD73 with ecto-5'-nucleotidase activity. | Heuts, DP., et al. 2012. Chembiochem. 13: 2384-91. PMID: 22997138
- Effect of NADP+ and its analogs on the Rose Bengal-sensitized photoinactivation of D-erythrulose reductase from beef liver. | Uehara, K., et al. 1979. J Biochem. 85: 1003-8. PMID: 37244
- Nicotinamide adenine dinucleotide as substrate of the nucleotide phosphotransferase from Escherichia coli. | Brunngraber, EF. and Chargaff, E. 1973. Biochemistry. 12: 3012-6. PMID: 4147175
- Studies on the polymer of adenosine diphosphate ribose. II. Characterization of the polymer. | Reeder, RH., et al. 1967. J Biol Chem. 242: 3172-9. PMID: 4291073
- Pyruvate carboxylase. Studies of activator-independent catalysis and of the specificity of activation by acyl derivatives of coenzyme A for the enzyme from rat liver. | Scrutton, MC. 1974. J Biol Chem. 249: 7057-67. PMID: 4612033
- Identification of competitive antagonists of the P2Y1 receptor. | Boyer, JL., et al. 1996. Mol Pharmacol. 50: 1323-9. PMID: 8913364
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Adenosine 2′,5′-diphosphate sodium salt, 5 mg | sc-214495 | 5 mg | $143.00 | |||
Adenosine 2′,5′-diphosphate sodium salt, 25 mg | sc-214495A | 25 mg | $469.00 |