Acridine Mutagen ICR 191 (CAS 17070-45-0)
QUICK LINKS
Acridine Mutagen ICR 191 or Icr-191, is a white crystalline solid that falls under the category of substituted polycyclic aromatic hydrocarbons (PAHs). With a molecular weight of 451.22 g/mol, it exhibits solubility in water. Extensive research has been conducted on Acridine Mutagen ICR 191 regarding its applications in scientific research, as well as its biochemical and physiological effects on human and animal cells. Acridine Mutagen ICR 191 has been extensively studied for its potential applications in scientific research. It serves as useful for investigating the impact of PAHs on human and animal cells, as well as exploring the mechanisms of action of diverse drugs. Furthermore, it aids in studying the environmental effects of PAHs and the biodegradation process. Acridine Mutagen ICR 191 functions as an inhibitor of the enzyme cytochrome P450, which plays a role in the metabolism of various compounds. It is also believed to interact with additional enzymes involved in drug and compound metabolism, such as cytochrome P450 reductase and cytochrome P450 oxidase.
Acridine Mutagen ICR 191 (CAS 17070-45-0) References
- An investigation of DNA mismatch repair capacity under normal culture conditions and under conditions of supra-physiological challenge in human CD4+T cell clones from donors of different ages. | Annett, K., et al. 2005. Exp Gerontol. 40: 976-81. PMID: 16216462
- Specificity of base substitutions induced by the acridine mutagen ICR-191: mispairing by guanine N7 adducts as a mutagenic mechanism. | Sahasrabudhe, SR., et al. 1991. Genetics. 129: 981-9. PMID: 1783299
- Attenuation of acridine mutagen ICR-191--DNA interactions and DNA damage by the mutagen interceptor chlorophyllin. | Pietrzak, M., et al. 2008. Biophys Chem. 135: 69-75. PMID: 18423964
- Induction of G.C to A.T transitions by the acridine half-mustard ICR-191 supports a mispairing mechanism for mutagenesis by some bulky mutagens. | Sahasrabudhe, SR., et al. 1990. Biochemistry. 29: 10899-905. PMID: 2271689
- Does C60 fullerene act as a transporter of small aromatic molecules? | Borowik, A., et al. 2018. Colloids Surf B Biointerfaces. 164: 134-143. PMID: 29413590
- Interactions of newly synthesized platinum nanoparticles with ICR-191 and their potential application. | Borowik, A., et al. 2019. Sci Rep. 9: 4987. PMID: 30899037
- The Impact of Surface Functionalization on the Biophysical Properties of Silver Nanoparticles. | Borowik, A., et al. 2019. Nanomaterials (Basel). 9: PMID: 31277307
- Genotoxicity and acute toxicity evaluation of the three amino acid additives with Corynebacterium glutamicum biomass. | Kang, KY., et al. 2020. Toxicol Rep. 7: 241-253. PMID: 32025500
- The First Report to Evaluate Safety of Cyanobacterium Leptolyngbya sp. KIOST-1 for Use as a Food Ingredient: Oral Acute Toxicity and Genotoxicity Study. | Lee, Y., et al. 2021. J Microbiol Biotechnol. 31: 290-297. PMID: 33203826
- Evaluation of the in vitro and in vivo genotoxicity of a Dioscorea Rhizome water extract. | Cha, SB., et al. 2021. Toxicol Res. 37: 385-393. PMID: 34295802
- Evaluation of Subchronic Toxicity and Genotoxicity of Ethanolic Extract of Aster glehni Leaves and Stems. | Lim, MK., et al. 2021. Evid Based Complement Alternat Med. 2021: 1018101. PMID: 35003288
- Toxicological evaluation of the red mold rice extract, ANKASCIN 568-R: 13-week chronic toxicity, and genotoxicity studies. | Lin, CW., et al. 2022. Toxicol Rep. 9: 356-365. PMID: 35284245
- Genetic characterization of ompH mutants in the deep-sea bacterium Photobacterium sp. strain SS9. | Bartlett, D. and Chi, E. 1994. Arch Microbiol. 162: 323-8. PMID: 7857197
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Acridine Mutagen ICR 191, 10 mg | sc-214486 | 10 mg | $155.00 | |||
Acridine Mutagen ICR 191, 25 mg | sc-214486A | 25 mg | $288.00 | |||
Acridine Mutagen ICR 191, 100 mg | sc-214486B | 100 mg | $883.00 |