Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Acinus Antibody (2005C3a) is a high quality monoclonal Acinus antibody (also designated Acinus antibody) suitable for the detection of the Acinus protein of human origin. Acinus Antibody (2005C3a) is available as the non-conjugated anti-Acinus antibody. The complex process of apoptosis requires the systematic activation of cysteine proteases, the condensation of chromatin and the fragmentation of DNA. Chromatin condensation occurs following the proteolytic activation of the caspases and the subsequent induction of the nuclear protein Acinus (apoptotic chromatin condensation inducer in the nucleus). Various isoforms of Acinus, which are generated from alternative splicing patterns, include AcinusL, AcinusS and AcinusS′. Acinus is ubiquitously expressed and predominantly localized to the nucleus, where it associates with both the nuclear membrane and the nucleoplasm. Combined in vitro and in vivo studies indicate that during apoptosis caspase-3 cleaves the carboxy-terminus of Acinus to generate the soluble protein p23, which is essential for inducing chromatin condensation.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.