Molecular structure of Acetylthiocholine chloride, CAS Number: 6050-81-3
Acetylthiocholine chloride (CAS 6050-81-3)
Alternate Names:
(2-Mercaptoethyl)trimethylammonium chloride acetate
Application:
Acetylthiocholine chloride is a substrate for acetylcholinesterase
CAS Number:
6050-81-3
Purity:
≥99%
Molecular Weight:
197.73
Molecular Formula:
C7H16NOS•Cl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Acetylthiocholine chloride is an AChE (acetylcholinesterase) substrate and AChR (nicotinic acetylcholine receptor) agonist. Acetylthiocholine chloride is a compound used in biochemical assays to measure cholinesterase activity. It serves as a substrate that is hydrolyzed by cholinesterase enzymes, producing thiocholine. Thiocholine then reacts with a chromogenic reagent to generate a colored product, allowing for spectrophotometric measurement.
Acetylthiocholine chloride (CAS 6050-81-3) References
- Critical evaluation of acetylthiocholine iodide and acetylthiocholine chloride as substrates for amperometric biosensors based on acetylcholinesterase. | Bucur, MP., et al. 2013. Sensors (Basel). 13: 1603-13. PMID: 23353142
- Palladium-copper nanowires-based biosensor for the ultrasensitive detection of organophosphate pesticides. | Song, D., et al. 2017. Anal Chim Acta. 982: 168-175. PMID: 28734356
- A colorimetric assay for acetylcholinesterase activity and inhibitor screening based on the thiocholine-induced inhibition of the oxidative power of MnO2 nanosheets on 3,3',5,5'-tetramethylbenzidine. | Sun, Y., et al. 2018. Mikrochim Acta. 185: 446. PMID: 30187211
- Thiocholine-triggered reaction in personal glucose meters for portable quantitative detection of organophosphorus pesticide. | Tang, W., et al. 2019. Anal Chim Acta. 1060: 97-102. PMID: 30902336
- High-performance electrochemical enzyme sensor for organophosphate pesticide detection using modified metal-organic framework sensing platforms. | Mahmoudi, E., et al. 2019. Bioelectrochemistry. 130: 107348. PMID: 31437810
- Light-accelerating oxidase-mimicking activity of black phosphorus quantum dots for colorimetric detection of acetylcholinesterase activity and inhibitor screening. | Ren, L., et al. 2021. Analyst. 145: 8022-8029. PMID: 33057486
- Peroxidase-mimicking Activity of PCN-222(Fe) for Colorimetric Sensing of Acetylcholinesterase Activity and Inhibition. | Xia, M., et al. 2021. Anal Sci. 37: 1023-1027. PMID: 33071263
- An insect acetylcholinesterase biosensor utilizing WO3/g-C3N4 nanocomposite modified pencil graphite electrode for phosmet detection in stored grains. | Bilal, S., et al. 2021. Food Chem. 346: 128894. PMID: 33422918
- New luminometric method for quantification of biological sulfur nucleophiles with the participation of 9-cyano-10-methylacridinium salt. | Ievtukhov, V., et al. 2022. Luminescence. 37: 208-219. PMID: 34766428
- Potentially tunable ratiometric electrochemiluminescence sensing based on conjugated polymer nanoparticle for organophosphorus pesticides detection. | He, Y., et al. 2022. J Hazard Mater. 432: 128699. PMID: 35325864
- A sensitive and stable acetylcholinesterase biosensor with TiO2 nanoparticles anchored on graphitic carbon nanofibers for determination of organophosphate pesticides. | Tao, S., et al. 2022. Anal Methods. 14: 2396-2404. PMID: 35666469
- Ternary heterostructures of 1D/2D/2D CuCo2S4/CuS/Ti3C2 MXene: Boosted amperometric sensing for chlorpyrifos. | Mi, Y., et al. 2022. J Hazard Mater. 438: 129419. PMID: 35780734
- Thermodynamic studies with acetylthiocholine on nicotinic receptors of mammalian skeletal muscle in vitro. | Banerjee, B. and Ganguly, DK. 1995. Biochem Pharmacol. 49: 1713-6. PMID: 7786312
Activator of:
AChR.Substrate of:
AChE.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Acetylthiocholine chloride, 1 g | sc-257066 | 1 g | $95.00 | |||
Acetylthiocholine chloride, 5 g | sc-257066A | 5 g | $356.00 |