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Acetylsalicylic Anhydride (CAS 1466-82-6)

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Alternate Names:
Contraflu; Pircan; Vigal
Application:
Acetylsalicylic Anhydride is impurity D of Acetylsalicylic Acid
CAS Number:
1466-82-6
Molecular Weight:
342.30
Molecular Formula:
C18H14O7
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Acetylsalicylic anhydride is primarily utilized in organic synthesis and chemical research, particularly for its role as an acetylation agent. This compound is instrumental in modifying the chemical structures of various substrates by introducing acetyl groups, which can alter physical, chemical, and biological properties. In research, acetylsalicylic anhydride is used to study the kinetics and mechanisms of acetylation reactions, providing insights into reaction conditions that optimize yield and selectivity. It is also employed in the synthesis of derivatives of salicylic acid for materials science applications, where these derivatives are evaluated for their potential in new material formulations. Additionally, acetylsalicylic anhydride is investigated for its utility in synthesizing compounds with potential industrial applications, including the development of performance chemicals and intermediates in the production of more complex molecules.


Acetylsalicylic Anhydride (CAS 1466-82-6) References

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  2. Soft known-value constraints for improved quantitation in multivariate curve resolution.  |  Akbari Lakeh, M., et al. 2020. Anal Chim Acta. 1105: 64-73. PMID: 32138927
  3. Quantitative determination by high-performance liquid chromatography of acetylsalicylic acid and related substances in tablets.  |  Verstraeten, A., et al. 1987. J Chromatogr. 388: 201-16. PMID: 3558647
  4. Isolation of salicylsalicylic acid, acetylsalicylsalicylic acid, and acetylsalicylic anhydride from aspirin tablets by extraction and high-pressure liquid chromatography.  |  Reepmeyer, JC. and Kirchhoefer, RD. 1979. J Pharm Sci. 68: 1167-9. PMID: 501542
  5. Solid-state acetylation of codeine phosphate by aspirin.  |  Galante, RN., et al. 1979. J Pharm Sci. 68: 1494-8. PMID: 529038
  6. Determination of related compounds in aspirin by liquid chromatography.  |  Pfeiffer, CD. and Pankey, JW. 1982. J Pharm Sci. 71: 511-4. PMID: 7097494
  7. Aspirin--a national survey III: Determination of impurities in bulk aspirin and aspirin formulations by high-pressure liquid chromatography and spectrophotometry.  |  Kirchhoefer, RD., et al. 1980. J Pharm Sci. 69: 550-3. PMID: 7381741
  8. [Determination of trace amounts of salicylic acid and acetylsalicylic acid in polopirin and other drugs containing acetylsalicylic acid].  |  Gołkiewicz, W. and Bartos, A. 1993. Acta Pol Pharm. 50: 143-7. PMID: 8030422
  9. Colorimetric analysis of immunogenic impurities in acetylsalicylic acid.  |  Bungaard, H. 1976. J Pharm Pharmacol. 28: 544-7. PMID: 8605
  10. Analysis of trace amounts of acetylsalicylic anhydride in acetylsalicylic acid.  |  Spitz, HD. 1977. J Chromatogr. 140: 131-3. PMID: 893628
  11. Determination of salicylic acid, acetylsalicylic anhydride and acetylsalicylsalicylic acid in acetylsalicylic acid by high performance liquid chromatography.  |  Jansson, SO. and Andersson, I. 1977. Acta Pharm Suec. 14: 161-70. PMID: 906833
  12. Application of gas-liquid chromatography and high-performance liquid chromatography to the analysis of trace amounts of salicylic acid, acetylsalicylic anhydride and acetylsalicylsalicylic acid in aspirin samples and aspirin formulations.  |  Ali, SL. 1976. J Chromatogr. 126: 651-63. PMID: 977701

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Acetylsalicylic Anhydride, 25 mg

sc-207257
25 mg
$207.00