Date published: 2026-4-3

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Acetylsalicylic Acid-d3 (CAS 921943-73-9)

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Alternate Names:
Aspirin-d3; 2-(Acetyl-2,2,2-d3-oxy)-benzoic Acid; Acetyl-d3-salicylic Acid
CAS Number:
921943-73-9
Molecular Weight:
183.18
Molecular Formula:
C9H5D3O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Acetylsalicylic Acid-d3, often recognized by its critical role within the realm of chemical research and analytical methodologies, stands as a deuterated variant of Acetylsalicylic Acid, distinguished by the substitution of hydrogen atoms with deuterium. This modification significantly enhances its utility in spectroscopic studies, particularly in Nuclear Magnetic Resonance (NMR) spectroscopy, allowing for more precise elucidation of molecular dynamics, interaction mechanisms, and the investigation of metabolic pathways in non-human studies. The introduction of deuterium atoms not only aids in reducing the background noise in spectroscopic analysis but also serves as a stable isotope label, facilitating the tracing of the Acetylsalicylic Acid′s biochemical transformations and interactions within complex systems. This makes Acetylsalicylic Acid-d3 useful in the development of new synthetic methodologies, the study of chemical stability, and the exploration of reaction mechanisms, underscoring its indispensable role in advancing scientific understanding in chemistry and biochemistry research landscapes.


Acetylsalicylic Acid-d3 (CAS 921943-73-9) References

  1. Innovative combination of QuEChERS extraction with on-line solid-phase extract purification and pre-concentration, followed by liquid chromatography-tandem mass spectrometry for the determination of non-steroidal anti-inflammatory drugs and their metabolites in sewage sludge.  |  Rossini, D., et al. 2016. Anal Chim Acta. 935: 269-81. PMID: 27543036
  2. Acetylation Blocks cGAS Activity and Inhibits Self-DNA-Induced Autoimmunity.  |  Dai, J., et al. 2019. Cell. 176: 1447-1460.e14. PMID: 30799039
  3. METTL3 acetylation impedes cancer metastasis via fine-tuning its nuclear and cytosolic functions.  |  Li, Y., et al. 2022. Nat Commun. 13: 6350. PMID: 36289222

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Acetylsalicylic Acid-d3, 10 mg

sc-480464
10 mg
$388.00