Molecular structure of Acetyl-L-threonine, CAS Number: 17093-74-2
Acetyl-L-threonine (CAS 17093-74-2)
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Alternate Names:
N-acetylthreonine; Ac-Thr-OH
CAS Number:
17093-74-2
Purity:
≥97%
Molecular Weight:
161.16
Molecular Formula:
C6H11NO4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Acetyl-L-threonine, also known as N-Acetylthreonine, is thought to exert its mechanism of action through the enzyme threonine acetyltransferase, responsible for catalyzing threonine′s acetylation process. This enzyme plays a role in regulating glucose and lipid metabolism, as well as influencing the immune system′s modulation. Additionally, Acetyl-L-threonine is believed to affect other enzymes, including histone acetyltransferases, which are essential for gene expression and epigenetic regulation.
Acetyl-L-threonine (CAS 17093-74-2) References
- Mutations in ACY1, the gene encoding aminoacylase 1, cause a novel inborn error of metabolism. | Sass, JO., et al. 2006. Am J Hum Genet. 78: 401-9. PMID: 16465618
- Gas chromatographic-mass spectrometric analysis of N-acetylated amino acids: the first case of aminoacylase I deficiency. | Gerlo, E., et al. 2006. Anal Chim Acta. 571: 191-9. PMID: 17723438
- N-acetylamino acid utilization by kidney aminoacylase-1. | Lindner, HA., et al. 2008. Biochimie. 90: 773-80. PMID: 18222180
- Prediction of Declining Renal Function and Albuminuria in Patients With Type 2 Diabetes by Metabolomics. | Solini, A., et al. 2016. J Clin Endocrinol Metab. 101: 696-704. PMID: 26684276
- Circulating Modified Metabolites and a Risk of ESRD in Patients With Type 1 Diabetes and Chronic Kidney Disease. | Niewczas, MA., et al. 2017. Diabetes Care. 40: 383-390. PMID: 28087576
- Respiratory Syncytial Virus and Rhinovirus Bronchiolitis Are Associated With Distinct Metabolic Pathways. | Stewart, CJ., et al. 2018. J Infect Dis. 217: 1160-1169. PMID: 29293990
- Pharmacometabolomics analysis of plasma to phenotype clopidogrel high on treatment platelets reactivity in coronary artery disease patients. | Amin, AM., et al. 2018. Eur J Pharm Sci. 117: 351-361. PMID: 29526765
- Metabolomic profiling to improve glomerular filtration rate estimation: a proof-of-concept study. | Coresh, J., et al. 2019. Nephrol Dial Transplant. 34: 825-833. PMID: 29718360
- Untargeted Metabolite Profiling of Cerebrospinal Fluid Uncovers Biomarkers for Severity of Late Infantile Neuronal Ceroid Lipofuscinosis (CLN2, Batten Disease). | Sindelar, M., et al. 2018. Sci Rep. 8: 15229. PMID: 30323181
- Metabolomics profiling and pathway analysis of human plasma and urine reveal further insights into the multifactorial nature of coronary artery disease. | Amin, AM., et al. 2019. Clin Chim Acta. 493: 112-122. PMID: 30826371
- Novel biomarkers of diabetic kidney disease: current status and potential clinical application. | Barutta, F., et al. 2021. Acta Diabetol. 58: 819-830. PMID: 33528734
- Global biochemical analysis of plasma, serum and whole blood collected using various anticoagulant additives. | Kennedy, AD., et al. 2021. PLoS One. 16: e0249797. PMID: 33831088
- CSF metabolites associate with CSF tau and improve prediction of Alzheimer's disease status. | Dong, R., et al. 2021. Alzheimers Dement (Amst). 13: e12167. PMID: 33969169
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Acetyl-L-threonine, 250 mg | sc-284929 | 250 mg | $162.00 | |||
Acetyl-L-threonine, 1 g | sc-284929A | 1 g | $318.00 |