Date published: 2025-10-15

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Acetyl-DL-phenylalanine beta-naphthyl ester (CAS 20874-31-1)

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Alternate Names:
2-Naphthyl N-acetylphenylalaninate; APNE
Application:
Acetyl-DL-phenylalanine beta-naphthyl ester is a chromogenic substrate for chymotrypsin
CAS Number:
20874-31-1
Molecular Weight:
333.39
Molecular Formula:
C21H19NO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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N-Acetyl-DL-phenylalanine beta-naphthyl ester (NAPNE) is a compound extensively utilized in scientific research and laboratory experiments due to its distinctive characteristics. Derived from the amino acid phenylalanine, Acetyl-DL-phenylalanine beta-naphthyl ester consists of a benzene ring with an attached acetyl group and naphthyl group. It serves as an enzyme inhibitor, possesses light absorption properties, and acts as a fluorescent probe. It has proven effective as an enzyme inhibitor, targeting enzymes like acetylcholinesterase and lipoxygenase, while also serving as a fluorescent probe for the detection of biological molecules. In terms of enzyme inhibition, N-Acetyl-DL-phenylalanine beta-naphthyl ester achieves this by binding to the active site of the enzyme, impeding its normal function. As a fluorescent probe, it absorbs light and emits light at a different wavelength, enabling the detection of biological molecules.Overall, the remarkable properties of N-Acetyl-DL-phenylalanine beta-naphthyl ester make it a valuable compound in scientific research, offering insights into diverse areas and paving the way for potential future advancements.


Acetyl-DL-phenylalanine beta-naphthyl ester (CAS 20874-31-1) References

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  5. Esterases of the polymorphonuclear leukocyte capable of hydrolyzing acetyl DL-phenyl-alanine beta-naphthyl ester. Relationship to the activatable esterase of chemotaxis.  |  Becker, EL. and Ward, PA. 1969. J Exp Med. 129: 569-84. PMID: 5812915
  6. Hydrolyses of alpha-naphthyl acetate, beta-naphthyl acetate, and acetyl-DL-phenylalanine beta-naphthyl ester.  |  Kirkeby, S. and Moe, D. 1983. Acta Histochem. 72: 225-31. PMID: 6410665
  7. Mutants of Salmonella typhimurium deficient in an endoprotease.  |  Miller, CG., et al. 1976. J Bacteriol. 127: 490-7. PMID: 776937
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Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Acetyl-DL-phenylalanine beta-naphthyl ester, 500 mg

sc-284910A
500 mg
$210.00

Acetyl-DL-phenylalanine beta-naphthyl ester, 1 g

sc-284910
1 g
$300.00