Molecular structure of Acetyl coenzyme A sodium salt, CAS Number: 102029-73-2
Acetyl coenzyme A trisodium salt (CAS 102029-73-2)
See product citations (3)
Alternate Names:
Acetyl coenzyme A trisodium salt is also known as Acetyl-CoA.
Application:
Acetyl coenzyme A trisodium salt is an essential cofactor, metabolic intermediate, and carrier of acyl groups.
CAS Number:
102029-73-2
Purity:
≥92%
Molecular Weight:
875.52
Molecular Formula:
C23H35N7O17P3SNa3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Acetyl coenzyme A trisodium salt (Acetyl-CoA) is an essential cofactor and carrier of acyl groups in enzymatic acetyl transfer reactions. It is formed either by the oxidative decarboxylation of pyruvate in mitochondria, by the oxidation of long-chain fatty acids, or by the oxidative degradation of certain amino acids. Acetyl coenzyme A trisodium salt is a key precursor in lipid biosynthesis, and the source of all fatty acid carbons. It′s also a positive regulator of pyruvate carboxylase and a precursor of the neurotransmitter acetylcholine. Acetyl coenzyme A trisodium salt is also known as Acetyl-CoA, Acethyl coenzyme alpha sodium salt, and S-acetate coenzyme A, trisodium salt.
Acetyl coenzyme A trisodium salt (CAS 102029-73-2) References
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- A chronic Alzheimer's model evoked by mitochondrial poison sodium azide for pharmacological investigations. | Szabados, T., et al. 2004. Behav Brain Res. 154: 31-40. PMID: 15302108
- Studies of the in vitro Nalpha-acetyltransferase activities of E. coli RimL protein. | Miao, L., et al. 2007. Biochem Biophys Res Commun. 357: 641-7. PMID: 17445774
- Electrochemical genotoxicity screening for arylamines bioactivated by N-acetyltransferase. | So, M., et al. 2008. Anal Chem. 80: 1192-200. PMID: 18189370
- Enzymatic immuno-assembly of gold nanoparticles for visualized activity screening of histone-modifying enzymes. | Zhen, Z., et al. 2012. Anal Chem. 84: 3614-20. PMID: 22455353
- Metabolic activation of CaMKII by coenzyme A. | McCoy, F., et al. 2013. Mol Cell. 52: 325-39. PMID: 24095281
- Molecular Basis of Substrate Specific Acetylation by N-Terminal Acetyltransferase NatB. | Hong, H., et al. 2017. Structure. 25: 641-649.e3. PMID: 28380339
- Characterization and quantitative analysis of related substances in Coenzyme A by HPLC and LC-MS/MS. | Yang, Y., et al. 2018. J Pharm Biomed Anal. 150: 220-232. PMID: 29253778
- (E)-2-Hexenal, as a Potential Natural Antifungal Compound, Inhibits Aspergillus flavus Spore Germination by Disrupting Mitochondrial Energy Metabolism. | Ma, W., et al. 2019. J Agric Food Chem. 67: 1138-1145. PMID: 30614691
- Overlap Concentration and the Effect of Macromolecular Crowding on Citrate Synthase Activity. | Wilcox, XE., et al. 2020. Biochemistry. 59: 1737-1746. PMID: 32216302
- Analysis of the mechanosensor channel functionality of TACAN. | Niu, Y., et al. 2021. Elife. 10: PMID: 34374644
- Biotin controls intestinal stem cell mitosis and host-microbiome interactions. | Neophytou, C. and Pitsouli, C. 2022. Cell Rep. 38: 110505. PMID: 35263602
- Benzidine activation in the Ames test: roles of hepatic N-acetyltransferase and other cytosolic and microsomal factors. | Light, HC., et al. 1987. Carcinogenesis. 8: 139-43. PMID: 3542272
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Inhibitor of:
FAHD2B, GLYATL1, GLYATL2, L-Glycerol-3-Phosphate Oxidase, MCCA, and PANK1.Activator of:
δ-FR, AASS, ACAA2, ACAD-12, ACOT10, ACOT3, ACSF4, ACSL5, ACSS3, ACSVL3, ADP ribosylation factor (ARF), Apolipoprotein L (ApoL), AUH, AWAT1, cHMGCS, chondroitin sulfate, CPN cat, CPS1, CROT, DGAT2L6, DHDPSL, E3BP, ECHDC1, ECHDC3, EG240549, EG628456, Eso-1, EXTL1, FAR2, Fatso, FDPS, FucT-VII, GDE1, GLYAT, GLYATL1, GLYCTK, GPD2, GRHPR, HAAO, HADHSC, HAL, HAO2, Headpin, HS6ST2, IDHC, IGHMBP2, IVD, LPAAT-β, MCAT, MCEE, ME3, MIPP, MMD2, NAA25, NANS, NAT-12, NAT-14, NAT-8L, OTA, PANK4, pantophysin, PBGS, PCMT1, PDH-E1β, PDSS1, PECR, POMGnT1, PPC-DC, pyridoxal kinase, SerRSmt, Sialyltransferase 7E, SOAT1, ST8Sia II, TIP47, UAP1, XylT-II, ZADH2, and ZUFSP.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Acetyl coenzyme A trisodium salt, 1 mg | sc-210745 | 1 mg | $47.00 | |||
Acetyl coenzyme A trisodium salt, 5 mg | sc-210745A | 5 mg | $92.00 | |||
Acetyl coenzyme A trisodium salt, 1 g | sc-210745B | 1 g | $5826.00 |