Date published: 2026-2-1

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Acetonitrile-15N (CAS 14149-39-4)

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Alternate Names:
Methyl cyanide-15N
CAS Number:
14149-39-4
Molecular Weight:
42.05
Molecular Formula:
C2H3(15N)
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Acetonitrile-15N is a stable, non-radioactive isotope of acetonitrile, a colorless liquid with a faint, sweet odor. It is used as a polar aprotic solvent in various biochemical applications, including peptide sequencing and DNA synthesis. Acetonitrile-15N is particularly in nuclear magnetic resonance (NMR) spectroscopy, where it is used as an internal standard for calibration and quantification of 15N-labeled compounds. Its unique isotopic composition makes it powerful for studying metabolic pathways and protein dynamics in living organisms. In biochemistry, acetonitrile-15N is a reagent for stable isotope labeling of biomolecules, allowing for precise tracking and analysis of biochemical processes. Its versatility and reliability make it becomes an indispensable component in biochemistry.


Acetonitrile-15N (CAS 14149-39-4) References

  1. Primary and secondary kinetic isotope effects in proton (H(+)/D(+)) and chloronium ion ((35)Cl(+)/(37)Cl(+)) affinities.  |  Gozzo, FC. and Eberlin, MN. 2001. J Mass Spectrom. 36: 1140-8. PMID: 11747108
  2. Generalizing, Extending, and Maximizing Nitrogen-15 Hyperpolarization Induced by Parahydrogen in Reversible Exchange.  |  Colell, JF., et al. 2017. J Phys Chem C Nanomater Interfaces. 121: 6626-6634. PMID: 28392884
  3. Quasi-Resonance Signal Amplification by Reversible Exchange.  |  Theis, T., et al. 2018. J Phys Chem Lett. 9: 6136-6142. PMID: 30284835
  4. Infrared spectra and structure of carbanions-XIII1: A study of the carbanions generated from acetonitrile, acetonitrile-d3 and acetonitrile-15n  |  Juchnovski, I. N., Dimitrova, J. S., Binev, I. G., & Kaneti, J. 1978. Tetrahedron. 34(6): 779-783.
  5. Infrared spectra of hydrogen-bonded complexes between methyl cyanide and hydrogen fluoride in solid argon at 12 K  |  Johnson, G. L., & Andrews, L. 1983. The Journal of Physical Chemistry. 87(11): 1852-1859.
  6. NMR Study of Blue-Shifting Hydrogen Bonds Formed by Fluoroform in Solution  |  Golubev, N. S., Denisov, G. S., Macholl, S., Smirnov, S. N., Shenderovich, I. G., & Tolstoy, P. M. 2008. Zeitschrift für Physikalische Chemie. 222(8-9): 1225-1245.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Acetonitrile-15N, 500 mg

sc-227199
500 mg
$737.00