Date published: 2025-10-6

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Acetamide (CAS 60-35-5)

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CAS Number:
60-35-5
Purity:
98%
Molecular Weight:
59.07
Molecular Formula:
C2H5NO
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Acetamide is utilized in research applications focusing on organic synthesis and catalysis. Acetamide serves as a versatile precursor in the synthesis of various chemicals, facilitating the introduction of the amide functionality into molecular structures. In catalytic studies, Acetamide is explored for its role as a ligand, particularly in reactions where non-aqueous media are required. Its properties are harnessed in the study of hydrogen bonding and molecular interactions.


Acetamide (CAS 60-35-5) References

  1. Acetamide.  |  . 1999. IARC Monogr Eval Carcinog Risks Hum. 71 Pt 3: 1211-21. PMID: 10476387
  2. Acetamide-induced liver cell alterations in rats.  |  DESSAU, FI. and JACKSON, B. 1955. Lab Invest. 4: 387-97. PMID: 13272304
  3. Acetamide hydrolyzing activity of Bacillus megaterium F-8 with bioremediation potential: optimization of production and reaction conditions.  |  Sogani, M., et al. 2014. Environ Sci Pollut Res Int. 21: 8822-30. PMID: 24723348
  4. Exposure Assessment of Acetamide in Milk, Beef, and Coffee Using Xanthydrol Derivatization and Gas Chromatography/Mass Spectrometry.  |  Vismeh, R., et al. 2018. J Agric Food Chem. 66: 298-305. PMID: 29186951
  5. Design, synthesis and biological evaluation of novel acetamide-substituted doravirine and its prodrugs as potent HIV-1 NNRTIs.  |  Wang, Z., et al. 2019. Bioorg Med Chem. 27: 447-456. PMID: 30606670
  6. Interactions of acetamide and acrylamide with heme models: Synthesis, infrared spectra, and solid state molecular structures of five- and six-coordinate ferric porphyrin derivatives.  |  Xu, N., et al. 2019. J Inorg Biochem. 194: 160-169. PMID: 30856456
  7. Non-Ionic Deep Eutectic Liquids: Acetamide-Urea Derived Room Temperature Solvents.  |  Suriyanarayanan, S., et al. 2019. Int J Mol Sci. 20: PMID: 31212745
  8. The food contaminant acetamide is not an in vivo clastogen, aneugen, or mutagen in rodent hematopoietic tissue.  |  Moore, MM., et al. 2019. Regul Toxicol Pharmacol. 108: 104451. PMID: 31470077
  9. Presence of Acetamide in Milk and Beef from Cattle Consuming AFEX-Treated Crop Residues.  |  Bals, B., et al. 2019. J Agric Food Chem. 67: 10756-10763. PMID: 31483626
  10. Potential of 2-Chloro-N-(4-fluoro-3-nitrophenyl)acetamide Against Klebsiella pneumoniae and In Vitro Toxicity Analysis.  |  Cordeiro, L., et al. 2020. Molecules. 25: PMID: 32877986
  11. Intrinsic acetamide brush-off by polyurea biodendrimers.  |  Martinho, N., et al. 2021. J Mater Chem B. 9: 3371-3376. PMID: 33881429
  12. Urea and Acetamide Rich Solutions Circumvent the Strand Inhibition Problem to Allow Multiple Rounds of DNA and RNA Copying.  |  Lozoya-Colinas, A., et al. 2022. Chembiochem. 23: e202100495. PMID: 34797020
  13. Biological effects of acetamide, formamide, and their monomethyl and dimethyl derivatives.  |  Kennedy, GL. 1986. Crit Rev Toxicol. 17: 129-82. PMID: 3530639
  14. Studies on the mechanism of acetamide hepatocarcinogenicity.  |  Dybing, E., et al. 1987. Pharmacol Toxicol. 60: 9-16. PMID: 3550769

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Acetamide, 100 g

sc-210737
100 g
$32.00

Acetamide, 500 g

sc-210737A
500 g
$77.00