ACDPP hydrochloride (CAS 37804-11-8)

ACDPP hydrochloride, scientifically known as 1-Amino-cyclopentane-1,3-dicarboxylic acid hydrochloride, is a specialized compound of significant interest in the field of neuropharmacology research, particularly for its role as a potent and selective antagonist at the metabotropic glutamate receptor group II (mGluR2/3). Its structure enables it to interact specifically with these receptor subtypes, offering a tool for dissecting the complex signaling pathways mediated by glutamatergic neurotransmission. ACDPP hydrochloride′s ability to bind to these receptors allows researchers to investigate the modulation of glutamate, the most abundant excitatory neurotransmitter in the vertebrate nervous system, and its implications for synaptic plasticity, memory formation, and neuronal excitability. In experimental applications, this compound is invaluable for studying the physiological and pathological roles of mGluR2/3 in various models of neurological conditions, contributing to the broader understanding of glutamate′s role in neurobiological processes. It serves as a critical tool in the exploration of the underlying mechanisms of action of metabotropic glutamate receptors and their potential as targets for novel therapeutic strategies in neurology and psychiatry.