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Ac-YVAD-pNA, a synthetic peptide, has gained significant popularity in scientific research owing to its remarkable ability to efficiently and rapidly inhibit caspases. Caspases, a family of cysteine proteases for apoptosis or programmed cell death, can be effectively targeted by Ac-YVAD-pNA. This peptide has emerged as an indispensable tool for studying apoptosis and investigating the roles of caspases in various diseases and disorders. Ac-YVAD-pNA exerts its inhibitory effects by binding to the active site of caspases, effectively preventing their substrate cleavage and impeding the initiation of apoptosis. Importantly, this inhibition is reversible and can be counteracted by the introduction of a reducing agent, such as dithiothreitol (DTT). Moreover, Ac-YVAD-pNA possesses the remarkable ability to simultaneously inhibit multiple caspases, rendering it an invaluable tool for examining the impact of caspase inhibition on intricate cell signaling pathways.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ac-YVAD-pNA, 1 mg | sc-311283 | 1 mg | $47.00 | |||
Ac-YVAD-pNA, 5 mg | sc-311283A | 5 mg | $114.00 |