Ac-VAD-pNA MF: C20H27N5O8
MW: 465
A chromogenic paranitroanilide substrate of caspase-1.

Ac-VAD-pNA

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Synonym: Acetyl-Val-Ala-Asp-p-Nitro-Anilide; Ac-Val-Ala-Asp-PNA
Application: A chromogenic paranitroanilide substrate of caspase-1
Molecular Weight: 465
Molecular Formula: C20H27N5O8
* Refer to Certificate of Analysis for lot specific data (including water content).
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Ac-VAD-pNA is a chromogenic paranitroanilide substrate of caspase-1. It is also cleaved by caspase-3, caspase-4, and caspase-7. Similar to amino acids 114-116 (VHD) of the IL-1B precursor, it is an anendogenous substrate of caspase-1. The release of pNA is monitored at 405 nm (ε=9.160M-1cm-1).

Physical State :
Solid
Solubility :
Soluble in DMSO, DMF, and aqueous buffers.
Storage :
Store at room temperature
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
MDL Number :
MFCD02259219

Download SDS (MSDS)

Certificate of Analysis

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