AC 55649 CAS: 59662-49-6
MF: C21H26O2
MW: 310.44
A potent, isoform-selective RARβ2 receptor agonist.

AC 55649 (CAS 59662-49-6)

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Alternate Names: 4'-Octyl-[1,1'-biphenyl]-4-carboxylic acid
Application: AC 55649 is a potent, isoform-selective RARβ2 receptor agonist
CAS Number: 59662-49-6
Purity: ≥98%
Molecular Weight: 310.44
Molecular Formula: C21H26O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

AC 55649 is a potent, isoform-selective RARβ2 receptor agonist (pEC50 values are 6.9, 5.7 and 5.6 at RARβ2, RARβ1 and RARα respectively) that displays 100-fold selectivity versus other retinoid receptors. Inhibits proliferation of the breast cancer cell line MCF-7.


References

1. Lund, B.W., et al. 2005. J. Med. Chem. 48: 7517-7519. PMID: 16302793
2. Lund, B.W., et al. 2009. J. Med. Chem. 52: 1540-1545. PMID: 19239230

Physical State :
Solid
Solubility :
Soluble to 100 mM in DMSO and to 25 mM in Ethanol
Storage :
Store at 4° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
1714884
SMILES :
CCCCCCCCC1=CC=C(C=C1)C2=CC=C(C=C2)C(=O)O

Download SDS (MSDS)

Certificate of Analysis

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