AC 264613 is a selective and potent PAR2 ( protease-activated receptor 2) agonist. Additionally, AC 264613 is noted to display no activity towards other PAR subtypes or at other receptors implicated in nociception and inflammation. Other reports have indicated that phosphatidylinositol hydrolysis (PI), moblization of Ca2+ and cellular proliferation in cell cultures are stimulated by AC 264613.
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2. Gardell, L.R., et al. 2008. J. Pharmacol. Exp. Ther. 327: 799-808. PMID: 18768780
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