Molecular structure of ABT 751, CAS Number: 141430-65-1
ABT 751 (CAS 141430-65-1)
Alternate Names:
N-[2-[(4-Hydroxyphenyl)amino]-3-pyridinyl]-4-methoxybenzenesulfonamide
Application:
ABT 751 is an inhibitor of microtubule polymerization
CAS Number:
141430-65-1
Molecular Weight:
371.41
Molecular Formula:
C18H17N3O4S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
ABT 751 is an inhibitor of microtubule polymerization that binds β-tubulin on the colchine site. This compound has been shown to block the cell cycle at G2M phase and induce apoptosis.
ABT 751 (CAS 141430-65-1) References
Hande et al (2006) The pharmacokinetics and safety of ABT-751, a novel, orally bioavailable sulfonamide antimitotic agent: results of a phase 1 study. Clin.Cancer Res. 12 2834.Inhibitor of:
α Tubulin, α1b Tubulin, γ Tubulin, γ2 Tubulin, MAP-1A, Op18, and Tubulin.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ABT 751, 10 mg | sc-361097 | 10 mg | $179.00 | |||
ABT 751, 50 mg | sc-361097A | 50 mg | $825.00 |