Molecular structure of Abacavir-d4, CAS Number: 1217731-56-0
Abacavir-d4 (CAS 1217731-56-0)
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Alternate Names:
(1S-cis)-4-[2-Amino-6-(cyclopropylamino-d4)-9H-purin-9-yl]-2-cyclopentene-1-methanol; 1592U89-d4; ABC-d4; Abacavir Stable Isotope
Application:
Abacavir-d4 is a nucleoside reverse transcriptase inhibitor (NRTI)
CAS Number:
1217731-56-0
Molecular Weight:
290.36
Molecular Formula:
C14H14D4N6O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
A labeled nucleoside reverse transcriptase inhibitor (NRTI).
Abacavir-d4 (CAS 1217731-56-0) References
- Abacavir-lamivudine-zidovudine vs indinavir-lamivudine-zidovudine in antiretroviral-naive HIV-infected adults: A randomized equivalence trial. | Staszewski, S., et al. 2001. JAMA. 285: 1155-63. PMID: 11231744
- Antiretroviral Drug Use in a Cross-Sectional Population Survey in Africa: NIMH Project Accept (HPTN 043). | Fogel, JM., et al. 2017. J Acquir Immune Defic Syndr. 74: 158-165. PMID: 27828875
- The validity of self-reported antiretroviral use in persons living with HIV: a population-based study. | Grabowski, MK., et al. 2018. AIDS. 32: 363-369. PMID: 29194115
- HIV-1 Tat and opioids act independently to limit antiretroviral brain concentrations and reduce blood-brain barrier integrity. | Leibrand, CR., et al. 2019. J Neurovirol. 25: 560-577. PMID: 31102185
- Population pharmacokinetics of abacavir and lamivudine in severely malnourished human immunodeficiency virus-infected children in relation to treatment outcomes. | Archary, M., et al. 2019. Br J Clin Pharmacol. 85: 2066-2075. PMID: 31141195
- Abacavir Exposure in Children Cotreated for Tuberculosis with Rifampin and Superboosted Lopinavir-Ritonavir. | Rabie, H., et al. 2020. Antimicrob Agents Chemother. 64: PMID: 32071055
- Determination of Antiviral Drugs and Their Metabolites Using Micro-Solid Phase Extraction and UHPLC-MS/MS in Reversed-Phase and Hydrophilic Interaction Chromatography Modes. | Fical, L., et al. 2021. Molecules. 26: PMID: 33917128
- Pharmacokinetics, Safety, and Tolerability of a Single Oral Dose of Abacavir/Dolutegravir/Lamivudine Combination Tablets in Healthy Japanese Study Participants. | Singh, RP., et al. 2021. Clin Pharmacol Drug Dev. 10: 985-993. PMID: 34265164
- 1592U89, a novel carbocyclic nucleoside analog with potent, selective anti-human immunodeficiency virus activity. | Daluge, SM., et al. 1997. Antimicrob Agents Chemother. 41: 1082-93. PMID: 9145874
- Abacavir. | Foster, RH. and Faulds, D. 1998. Drugs. 55: 729-36; discussion 737-8. PMID: 9585869
Inhibitor of:
HIV-1 RT.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Abacavir-d4, 1 mg | sc-217548 | 1 mg | $350.00 | |||
Abacavir-d4, 10 mg | sc-217548A | 10 mg | $2800.00 |