Molecular structure of Abacavir Carboxylate, CAS Number: 384380-52-3
Abacavir Carboxylate (CAS 384380-52-3)
Application:
Abacavir Carboxylate is a nucleoside reverse transcriptase inhibitor (NRTI)
CAS Number:
384380-52-3
Purity:
98%
Molecular Weight:
300.32
Molecular Formula:
C14H16N6O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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A major metabolite of Abacavir
Abacavir Carboxylate (CAS 384380-52-3) References
- Pharmacokinetics of [(14)C]abacavir, a human immunodeficiency virus type 1 (HIV-1) reverse transcriptase inhibitor, administered in a single oral dose to HIV-1-infected adults: a mass balance study. | McDowell, JA., et al. 1999. Antimicrob Agents Chemother. 43: 2855-61. PMID: 10582871
- Pharmacokinetic interaction of abacavir (1592U89) and ethanol in human immunodeficiency virus-infected adults. | McDowell, JA., et al. 2000. Antimicrob Agents Chemother. 44: 1686-90. PMID: 10817729
- Abacavir pharmacokinetics during chronic therapy in HIV-1-infected adolescents and young adults. | Sleasman, JW., et al. 2009. Clin Pharmacol Ther. 85: 394-401. PMID: 19118380
- Development and validation of the first liquid chromatography-tandem mass spectrometry assay for simultaneous quantification of multiple antiretrovirals in meconium. | Himes, SK., et al. 2013. Anal Chem. 85: 1896-904. PMID: 23256731
- Abacavir pharmacogenetics--from initial reports to standard of care. | Martin, MA. and Kroetz, DL. 2013. Pharmacotherapy. 33: 765-75. PMID: 23649914
- Trends in sample preparation and separation methods for the analysis of very polar and ionic compounds in environmental water and biota samples. | Knoll, S., et al. 2020. Anal Bioanal Chem. 412: 6149-6165. PMID: 32710277
- Antiviral drugs in wastewater are on the rise as emerging contaminants: A comprehensive review of spatiotemporal characteristics, removal technologies and environmental risks. | Wang, R., et al. 2023. J Hazard Mater. 457: 131694. PMID: 37269566
- Recent Developments in Semiconductor-Based Photocatalytic Degradation of Antiviral Drug Pollutants. | Zhang, Z., et al. 2023. Toxics. 11: PMID: 37624197
- Clinical pharmacology of HIV protease inhibitors: focus on saquinavir, indinavir, and ritonavir. | Hoetelmans, RM., et al. 1997. Pharm World Sci. 19: 159-75. PMID: 9297727
- Chemotherapeutic agents for human immunodeficiency virus infection: mechanism of action, pharmacokinetics, metabolism, and adverse reactions. | Beach, JW. 1998. Clin Ther. 20: 2-25; discussion l. PMID: 9522101
Inhibitor of:
HIV-1 RT.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Abacavir Carboxylate, 1 mg | sc-210732 | 1 mg | $380.00 |