Molecular structure of AB-MECA, CAS Number: 152918-26-8
AB-MECA (CAS 152918-26-8)
Application:
AB-MECA is a high affinity A3 adenosine receptor agonist
CAS Number:
152918-26-8
Molecular Weight:
399.40
Molecular Formula:
C18H21N7O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
This is a high affinity A3 adenosine receptor agonist.
AB-MECA (CAS 152918-26-8) References
- First Synthesis of beta-D-Galf(1-4)GlcNAc, a Structural Unit Attached O-Glycosidically in Glycoproteins of Trypanosoma cruzi. | Gallo-Rodriguez, C., et al. 1996. J Org Chem. 61: 1886-1889. PMID: 11667072
- A(2B) adenosine receptors stimulate growth of porcine and rat arterial endothelial cells. | Dubey, RK., et al. 2002. Hypertension. 39: 530-5. PMID: 11882603
- Adenosine induces inositol 1,4,5-trisphosphate receptor-mediated mobilization of intracellular calcium stores in basal forebrain cholinergic neurons. | Basheer, R., et al. 2002. J Neurosci. 22: 7680-6. PMID: 12196591
- Adenosine and sleep deprivation promote NF-kappaB nuclear translocation in cholinergic basal forebrain. | Ramesh, V., et al. 2007. J Neurochem. 100: 1351-63. PMID: 17316404
- The role of adenosine receptors in regulating production of tumour necrosis factor-alpha and chemokines by human lung macrophages. | Buenestado, A., et al. 2010. Br J Pharmacol. 159: 1304-11. PMID: 20136829
- Interaction of SSR161421, a novel specific adenosine A(3) receptor antagonist with adenosine A(3) receptor agonists both in vitro and in vivo. | Mikus, EG., et al. 2013. Eur J Pharmacol. 699: 62-6. PMID: 23219789
- Evaluation of SSR161421, a novel orally active adenosine A3 receptor antagonist on pharmacology models. | Mikus, EG., et al. 2013. Eur J Pharmacol. 699: 172-9. PMID: 23219796
- Pharmacological Study of A3 Adenosine Receptor agonist (AB Meca) in Xenograft Lung Cancer Model in Mice through In Silico and In Vivo Approach: Targeting TNF-α. | Solanki, N., et al. 2022. Curr Drug Discov Technol. 19: e140122195498. PMID: 35135461
- 125I-4-aminobenzyl-5'-N-methylcarboxamidoadenosine, a high affinity radioligand for the rat A3 adenosine receptor. | Olah, ME., et al. 1994. Mol Pharmacol. 45: 978-82. PMID: 8190112
- A role for central A3-adenosine receptors. Mediation of behavioral depressant effects. | Jacobson, KA., et al. 1993. FEBS Lett. 336: 57-60. PMID: 8262217
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
AB-MECA, 1 mg | sc-239176 | 1 mg | $84.00 |