Molecular structure of A-779, CAS Number: 159432-28-7 (net)
A-779 (CAS 159432-28-7 (net))
See product citations (4)
Alternate Names:
DRVYIHA
Application:
A-779 is a selective angiotensin-(1-7) antagonist
CAS Number:
159432-28-7 (net)
Molecular Weight:
872.99
Molecular Formula:
C39H60N12O11
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
A-779 is a selective angiotensin-(1-7) antagonist. The peptide shows affinity for Mas receptor with an IC50 of 0.3 nM. A-779 is also an antidiuretic and vasoconstrictor agent.
A-779 (CAS 159432-28-7 (net)) References
Xue H et al. Counteraction between angiotensin II and angiotensin-(1-7) via activating angiotensin type I and Mas receptor on rat renal mesangial cells. Regul Pept 177:12-20 (2012).Maia LG et al. Angiotensin-(1-7) antagonist A-779 attenuates the potentiation of bradykinin by captopril in rats. J Cardiovasc Pharmacol 43:685-91 (2004).
Santos RA et al. Characterization of a new angiotensin antagonist selective for angiotensin-(1-7): evidence that the actions of angiotensin-(1-7) are mediated by specific angiotensin receptors. Brain Res Bull 35:293-8 (1994).
Inhibitor of:
Angiotensin.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
A-779, 1 mg | sc-396002 | 1 mg | $154.00 |