Molecular structure of A 1070722, CAS Number: 1384424-80-9
A 1070722 (CAS 1384424-80-9)
Alternate Names:
1-(7-Methoxyquinolin-4-yl)-3-[6-(trifluoromethyl)pyridin-2-yl]urea
Application:
A 1070722 is an inhibitor of GSK-3α and GSK-3β with a Ki = 0.6 nM respectively
CAS Number:
1384424-80-9
Molecular Weight:
362.31
Molecular Formula:
C17H13F3N4O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
A 1070722 is an inhibitor of GSK-3α and GSK-3β with a Ki = 0.6 nM for both isoforms. In addition, A 1070722 displays greater than 50-fold selectivity towards GSK3 than other protein kinases such as CDK. In vitro studies indicate that A 1070722 reduces phosphorylation of microtubule-associated protein Tau.
Inhibitor of:
GSK-3 alpha.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
A 1070722, 10 mg | sc-364392 | 10 mg | $131.00 | |||
A 1070722, 50 mg | sc-364392A | 50 mg | $709.00 |