9(S)-HETE (CAS 107656-13-3)

9(S)-HETE, with the CAS number 107656-13-3, is a specific enantiomer of hydroxyeicosatetraenoic acid distinguished by the presence of a hydroxyl group at the ninth carbon in the S configuration. This lipid mediator is a product of the oxygenation of arachidonic acid, primarily catalyzed by the enzyme 9-lipoxygenase. As a biologically active compound, 9(S)-HETE is involved in various intracellular signaling pathways that modulate cellular functions including proliferation, differentiation, and response to environmental stimuli. In research, 9(S)-HETE is utilized to investigate the role of lipoxygenase metabolites in cellular communication and regulation. Its specific actions include influencing the regulation of calcium ions within cells and affecting the activity of several key signaling proteins. These interactions are critical for understanding how cells adapt to changes in their environment and manage stress responses. Research involving 9(S)-HETE has provided valuable insights into the complex pathways of lipid signaling that contribute to cellular homeostasis and the mechanisms by which cells respond to oxidative stress. This research is vital for elucidating the underlying processes that govern cellular behavior in various biological contexts, enhancing our understanding of cell biology and the complex web of signaling networks.