Date published: 2025-10-17

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9-Oxofolic Acid (CAS 39707-61-4)

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Alternate Names:
N-[4-[[(2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)carbonyl]amino]benzoyl]-L-glutamic Acid
CAS Number:
39707-61-4
Molecular Weight:
455.38
Molecular Formula:
C19H17N7O7
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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9-Oxofolic Acid is a compound that functions as a key intermediate in the biosynthesis of tetrahydrofolate, a crucial coenzyme involved in one-carbon transfer reactions. Within the experimental applications, it serves as a precursor in the de novo synthesis of folate derivatives, playing a role in the production of essential biomolecules such as nucleotides and amino acids. Its mechanism of action involves participating in enzymatic reactions that lead to the formation of active folate coenzymes, which are essential for various cellular processes. 9-Oxofolic Acid undergoes reduction to form tetrahydrofolate, which then acts as a coenzyme in the transfer of one-carbon units for the synthesis of DNA, RNA, and other important cellular components. 9-Oxofolic Acid′s involvement in the folate biosynthetic pathway may be a significant player in the generation of biomolecules necessary for cellular function and growth.


9-Oxofolic Acid (CAS 39707-61-4) References

  1. Synthesis of pteridine-6-carboxamides. 9-Oxofolic acid and 9-oxoaminopterin  |  Nair, M. G., & Baugh, C. M. 1973. The Journal of Organic Chemistry. 38(12): 2185-2189.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

9-Oxofolic Acid, 5 mg

sc-478728
5 mg
$398.00

9-Oxofolic Acid, 50 mg

sc-478728A
50 mg
$2856.00