Molecular structure of 9-keto Fluprostenol, CAS Number: 156406-33-6
9-keto Fluprostenol (CAS 156406-33-6)
Alternate Names:
Fluprostenol Prostaglandin E2
Application:
9-keto Fluprostenol is an analog of prostaglandin E2
CAS Number:
156406-33-6
Molecular Weight:
456.5
Molecular Formula:
C23H27F3O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
An analog of prostaglandin E2 (PGE2) with structural modifications intended to give greater potency and a prolonged half-life. Fluprostenol is a well-studied, potent analog of PGF2α and acts primarily through the FP receptor.1 Oxidation at C-9 of fluprostenol yields 9-keto fluprostenol. It is anticipated that this analog will have strong affinity for EP receptors and act as a PGE2 agonist, however, no studies on the compound′s pharmacology have been published to date.
9-keto Fluprostenol (CAS 156406-33-6) References
- Effect of femto to nano molar concentrations of prostaglandin analogues on pregnant rat uterine contractility. | Khan, AH., et al. 2008. Eur J Pharmacol. 581: 185-90. PMID: 18177857
- Augmented Angiogenic Factors Expression via FP Signaling Pathways in Peritoneal Endometriosis. | Rakhila, H., et al. 2016. J Clin Endocrinol Metab. 101: 4752-4763. PMID: 27726474
- Potent luteolytic agents related to prostaglandin F2alpha. | Dukes, M., et al. 1974. Nature. 250: 330-1. PMID: 4853720
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
9-keto Fluprostenol, 1 mg | sc-205186 | 1 mg | $69.00 | |||
9-keto Fluprostenol, 5 mg | sc-205186A | 5 mg | $315.00 |