Molecular structure of 9-Aminoacridine hydrochloride, CAS Number: 52417-22-8
9-Aminoacridine hydrochloride (CAS 52417-22-8)
Alternate Names:
9-Acridinamine hydrochloride hydrate
Application:
9-Aminoacridine hydrochloride is a known mutagen
CAS Number:
52417-22-8
Purity:
≥98%
Molecular Weight:
230.69
Molecular Formula:
C13H10N2•HCl
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
9-Aminoacridine hydrochloride is a fluorescent dye in biochemistry and molecular biology. It is able to intercalate into DNA, making it useful for studying nucleic acid structure and function. 9-Aminoacridine hydrochloride binds to DNA and RNA, affecting their structure and stability. 9-Aminoacridine hydrochloride inhibits the activity of topoisomerase enzymes, which are involved in DNA replication and transcription.9-Aminoacridine hydrochloride is used in the study of DNA damage and repair mechanisms, as well as in the development of new methods for detecting and quantifying nucleic acids. Its fluorescent properties make it a useful probe for visualizing DNA and RNA in cells and tissues.
9-Aminoacridine hydrochloride (CAS 52417-22-8) References
- Nucleic acid-mutagen interactions: crystal structure of adenylyl-3',5'-uridine plus 9-aminoacridine. | Seeman, NC., et al. 1975. Nature. 253: 324-7. PMID: 1110774
- Excimer of 9-aminoacridine hydrochloride hydrate in confined medium: an integrated experimental and theoretical study. | Mitra, P., et al. 2013. J Phys Chem A. 117: 1428-38. PMID: 23346864
- Antibacterial efficacy of acridine derivatives conjugated with gold nanoparticles. | Mitra, P., et al. 2014. Int J Pharm. 473: 636-43. PMID: 25087507
- In vivo comet assay of acrylonitrile, 9-aminoacridine hydrochloride monohydrate and ethanol in rats. | Nakagawa, Y., et al. 2015. Mutat Res Genet Toxicol Environ Mutagen. 786-788: 104-13. PMID: 26212299
- Antibacterial and Photocatalytic Properties of ZnO-9-Aminoacridine Hydrochloride Hydrate Drug Nanoconjugates. | Mitra, P., et al. 2018. ACS Omega. 3: 7962-7970. PMID: 30087929
- Excimer emission in 9-aminoacridine hydrochloride | P. Gangola, N.B. Joshi, D.D. Pant. 1981. Chemical Physics Letters. 80: 418-421.
- A spectroscopic investigation of the photophysical behaviour of 9-aminoacridine hydrochloride hydrate in presence of organic amines in homogeneous and heterogeneous media | Piyali Mitra a, Brotati Chakraborty b, Samita Basu a. 2014. Journal of Luminescence. 149: 221-230.
- Exploring photoinduced electron transfer and excited-state proton transfer reactions involving 9-aminoacridine hydrochloride hydrate and methyl viologen using laser flash photolysis | Piyali Mitra a, Brotati Chakraborty b, Samita Basu a. 2014. Chemical Physics Letters. 610–611: 108-114.
- Identification of modes of interactions between 9-aminoacridine hydrochloride hydrate and serum proteins by low and high resolution spectroscopy and molecular modeling† | Piyali Mitraa, Uttam Palb, Nakul Chandra Maitib, Anirban Ghoshc, Anirban Bhuniac and Samita Basu*a. 2016. RSC Adv. 6: 53454-53468.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
9-Aminoacridine hydrochloride, 5 g | sc-214431 | 5 g | $33.00 | |||
9-Aminoacridine hydrochloride, 25 g | sc-214431A | 25 g | $83.00 |