Molecular structure of 9,12-Octadecadiynoic Acid, CAS Number: 2012-14-8
9,12-Octadecadiynoic Acid (CAS 2012-14-8)
Alternate Names:
Ro 3-1314
Application:
9,12-Octadecadiynoic Acid is an inhibitor of Cox and LO
CAS Number:
2012-14-8
Molecular Weight:
276.4
Molecular Formula:
C18H28O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
9,12-Octadecadiynoic Acid is an inhibitor of both Cox and LO (lipoxygenase). 9,12-Octadecadiynoic Acid inhibits ram seminal vesicle Cox with a Ki of 0.6 μM. It is a more effective inhibitor of Cox-1 than of 15-LO, inhibiting 95% and 68%, respectively, of these enzymatic activities when used at a concentration of 48 μM.
9,12-Octadecadiynoic Acid (CAS 2012-14-8) References
1 Vanderhoek, J.Y., Lands, W.E.M. Acetylenic inhibitors of sheep vesicular gland oxygenase. Biochim Biophys Acta 296 374-381 (1973). 2 Downing, D.T., Barve, J.A., Gunstone, F.D., et al. Structural requirements of acetylenic fatty acids for inhibition of soybean lipoxygenase and prostaglandin synthase. Biochim Biophys Acta 280 343-347 (1972).Inhibitor of:
15-LO.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
9,12-Octadecadiynoic Acid, 1 mg | sc-205191 | 1 mg | $80.00 | |||
9,12-Octadecadiynoic Acid, 5 mg | sc-205191A | 5 mg | $360.00 |