Date published: 2026-4-24

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9,10-Dihydrophenanthrene (CAS 776-35-2)

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CAS Number:
776-35-2
Molecular Weight:
180.25
Molecular Formula:
C14H12
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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9,10-Dihydrophenanthrene is a polycyclic hydrocarbon of interest primarily in organic and environmental chemistry research. Its structure, representing a partially saturated version of phenanthrene, makes it a useful model compound for studying the hydrogenation and aromatic stabilization energies of polycyclic aromatic hydrocarbons (PAHs). In environmental studies, it is often used as a non-aromatic analogue to understand the persistence and degradation pathways of PAHs in the soil and water, which are critical for assessing environmental contamination and remediation strategies. Additionally, chemists utilize 9,10-Dihydrophenanthrene to investigate the mechanisms of electrophilic aromatic substitution reactions, providing valuable insights into the synthesis of complex organic molecules.


9,10-Dihydrophenanthrene (CAS 776-35-2) References

  1. Photophysical and photochemical processes of 9,10-dihydro-9-silaphenanthrene derivatives: photochemical formation and electronic structure of 9-silaphenanthrenes.  |  Hiratsuka, H., et al. 2006. J Phys Chem A. 110: 3868-74. PMID: 16539407
  2. 9, 10-Dihydrophenanthrene derivatives from Pholidota yunnanensis and scavenging activity on DPPH free radical.  |  Guo, XY., et al. 2007. J Asian Nat Prod Res. 9: 165-74. PMID: 17454314
  3. Nickel-catalyzed [2+2+2] cycloaddition of arynes and an unactivated alkene: synthesis of 9,10-dihydrophenanthrene derivatives.  |  Saito, N., et al. 2009. Chem Commun (Camb). 4284-6. PMID: 19585048
  4. A new 9,10-dihydrophenanthrene and cell proliferative 3,4-δ-dehydrotocopherols from Stemona tuberosa.  |  Kil, YS., et al. 2015. Molecules. 20: 5965-74. PMID: 25854758
  5. A new 9,10-dihydrophenanthrene from Dendrobium moniliforme.  |  Zhao, N., et al. 2016. Nat Prod Res. 30: 174-9. PMID: 26132274
  6. New phenanthrene and 9, 10-dihydrophenanthrene derivatives from the stems of Dendrobium officinale with their cytotoxic activities.  |  Zhao, GY., et al. 2018. J Nat Med. 72: 246-251. PMID: 29063360
  7. A new phenanthrene and a new 9,10-dihydrophenanthren from Bulbophyllum retusiusculum.  |  Sun, J., et al. 2018. Nat Prod Res. 32: 2447-2451. PMID: 29284299
  8. Isolation, Structural Elucidation, Optical Resolution, and Antineuroinflammatory Activity of Phenanthrene and 9,10-Dihydrophenanthrene Derivatives from Bletilla striata.  |  Zhou, D., et al. 2019. J Nat Prod. 82: 2238-2245. PMID: 31415170
  9. Phenanthrene, 9,10-dihydrophenanthrene and bibenzyl enantiomers from Bletilla striata with their antineuroinflammatory and cytotoxic activities.  |  Sun, MH., et al. 2021. Phytochemistry. 182: 112609. PMID: 33326906
  10. Discovery of 9,10-dihydrophenanthrene derivatives as SARS-CoV-2 3CLpro inhibitors for treating COVID-19.  |  Zhang, JW., et al. 2022. Eur J Med Chem. 228: 114030. PMID: 34883292
  11. Rational identification of small molecules derived from 9,10-dihydrophenanthrene as potential inhibitors of 3CLpro enzyme for COVID-19 therapy: a computer-aided drug design approach.  |  Daoui, O., et al. 2022. Struct Chem. 33: 1667-1690. PMID: 35818588
  12. The anti-SARS-CoV-2 activity of novel 9, 10-dihydrophenanthrene derivatives: an insight into molecular docking, ADMET analysis, and molecular dynamics simulation.  |  Yamari, I., et al. 2023. Sci Afr. 21: e01754. PMID: 37332393
  13. Synthesis and antimalarial evaluation of 9,10-dihydrophenanthrene amino alcohols.  |  Dey, AS. and Neumeyer, JL. 1974. J Med Chem. 17: 1095-100. PMID: 4608227
  14. Antimicrobial activity of juncusol, a novel 9-10-dihydrophenanthrene from the marsh plant Juncus roemerianus.  |  Chapatwala, KD., et al. 1981. Life Sci. 29: 1997-2001. PMID: 6796796
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Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

9,10-Dihydrophenanthrene, 5 g

sc-254920
5 g
$106.00