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9,10-dihydro-15-deoxy-δ12,14-Prostaglandin J2 (CAS 596104-94-8)

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CAS Number:
596104-94-8
Molecular Weight:
318.5
Molecular Formula:
C20H30O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Designed as an analog of the PPARγ-binding prostaglandins which could not undergo this conjugation reaction. In human neuroblastoma SH-SY5Y cells, compound was not cytotoxic at up to 25 µM. Failed to covalently modify thioredoxin or induce oxidative stress at 50 µM.3


9,10-dihydro-15-deoxy-δ12,14-Prostaglandin J2 (CAS 596104-94-8) References

1 Forman, B.M., Tontonoz, P., Chen, J., et al. 15-Deoxy-Δ12,14-prostaglandin J2 is a ligand for the adipocyte determination factor PPARγ Cell 83, 803-812 (1995). 2 Atsmon, J., Sweetman, B.J., Baertschi, S.W., et al. Formation of thiol conjugates of 9-deoxy-Δ9,Δ12(E)-prostaglandin D2 and Δ12(E)-prostaglandin D2. Biochemistry 29 3760-3765 (1990). 3 Shibata, T., Yamada, T., Ishii, T., et al. Thioredoxin as a molecular target of cyclopentenone prostaglandins. J Biol Chem 278(28) 26046-26054 (2003).

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

9,10-dihydro-15-deoxy-Δ12,14-Prostaglandin J2, 500 µg

sc-223760
500 µg
$91.00

9,10-dihydro-15-deoxy-Δ12,14-Prostaglandin J2, 1 mg

sc-223760A
1 mg
$172.00