8-Oxo-2′-deoxyadenosine (CAS 62471-63-0)
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8-Oxo-2′-deoxyadenosine, also referred to as 8-oxo-dG, is a modified nucleoside generated through the oxidation of deoxyguanosine. As a vital biomarker of oxidative stress and DNA damage, it holds significance in scientific research. Its involvement has been noted in various diseases, such as cancer, neurodegenerative diseases, cardiovascular diseases, and aging processes. In scientific investigations, 8-Oxo-2′-deoxyadenosine has been extensively employed. Its role in the formation of DNA adducts, which can lead to mutations and DNA damage, remains not completely understood. Moreover, it influences gene expression, protein function, and impacts cellular processes. Specifically, it induces cell death, hinders cell proliferation, and activates DNA repair pathways. Additionally, it affects mitochondrial function and oxidative phosphorylation. Consequently, 8-Oxo-2′-deoxyadenosine serves as a valuable marker for assessing oxidative stress, DNA damage, and their implications in various biological applications.
8-Oxo-2′-deoxyadenosine (CAS 62471-63-0) References
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
8-Oxo-2′-deoxyadenosine, 10 mg | sc-477846 | 10 mg | $380.00 |