Molecular structure of 8-iso Prostaglandin F2α Ethanolamide
8-iso Prostaglandin F2α Ethanolamide
Alternate Names:
N-(2-hydroxyethyl)-9α,11α,15S-trihydroxy-(8β)-prosta-5Z,13E-dien-1-amide; iPF2α-III Ethanolamide; 8-Isoprostane Ethanolamide
Molecular Weight:
397.55
Molecular Formula:
C22H39NO5
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Its been reported that anandamide (AEA) can be used directly by cyclooxygenase-2 and specific prostaglandin H2 (PGH2) isomerases to produce ethanolamide congeners of the classical PGs, including PGF2α.(1) PGF2α. Ethanolamide has also been reported to be biosynthesized by this mechanism when AEA was infused into the lung and liver of fatty acid amide hydrolase-deficient mice(2). The accumulation of AEA can also lead to isoprostane-type peroxidative decomposition. 8-iso PGF2α ethanolamide is a standard that allows one to distinguish these non-enzymatic decomposition products from "prostamides" that possible have enzymatic origin.
8-iso Prostaglandin F2α Ethanolamide References
1 Bachur, N.R., Masek, K., Melmon, K.L., et al. Fatty acid amides of ethanolamine in mammalian tissues. J Biol Chem 240 1019-1024 (1965). 2 Weber, A., Ni, J., Ling, K.J., et al. Formation of prostamides from anandamide in FAAH knockout mice analyzed HPLOrdering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
8-iso Prostaglandin F2α Ethanolamide, 100 µg | sc-221140 | 100 µg | $49.00 | |||
8-iso Prostaglandin F2α Ethanolamide, 500 µg | sc-221140A | 500 µg | $222.00 | |||
8-iso Prostaglandin F2α Ethanolamide, 1 mg | sc-221140B | 1 mg | $420.00 |