Molecular structure of 8-iso Prostaglandin E2 isopropyl ester
8-iso Prostaglandin E2 isopropyl ester
Application:
8-iso Prostaglandin E2 isopropyl ester is which has shown both vasoconstriction and vasodilation activity
Molecular Weight:
394.6
Molecular Formula:
C23H38O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
8-iso Prostaglandin E2 isopropyl ester is a more lipophillic derivative of 8-iso PGE2 (sc-205172) which is the epimer at C-8 of PGE2 (sc-201225), which has shown both vasoconstriction and vasodilation activity (depending on the tissue). This compound is believed to be hydrolyzed to the free acid under physiological conditions, ultimately yielding 8-iso PGE2. These prostaglandin analogues are integral for structure-activity studies used in the deconvolution of these complex biochemical pathways.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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8-iso Prostaglandin E2 isopropyl ester References
- Actions of the E2-isoprostane, 8-ISO-PGE2, on the platelet thromboxane/endoperoxide receptor in humans and rats: additional evidence for the existence of a unique isoprostane receptor. | Longmire, AW., et al. 1994. Prostaglandins. 48: 247-56. PMID: 7878192
- Free radical-induced generation of isoprostanes in vivo. Evidence for the formation of D-ring and E-ring isoprostanes. | Morrow, JD., et al. 1994. J Biol Chem. 269: 4317-26. PMID: 8307999
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
8-iso Prostaglandin E2 isopropyl ester, 1 mg | sc-221136 | 1 mg | $89.00 | |||
8-iso Prostaglandin E2 isopropyl ester, 5 mg | sc-221136A | 5 mg | $403.00 |