Molecular structure of 8-iso Prostaglandin A2, CAS Number: 474391-66-7
8-iso Prostaglandin A2 (CAS 474391-66-7)
Alternate Names:
8-epi PGA2; 9-oxo-15S-hydroxy-(8β)-prosta-5Z,10,13E-trien-1-oic acid
Application:
8-iso Prostaglandin A2 is a prostaglandin like compound produced by peroxidation of arachidonoyl-containing lipids
CAS Number:
474391-66-7
Purity:
≥98%
Molecular Weight:
334.5
Molecular Formula:
C20H30O4
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Isoprostanes are prostaglandin (PG)-like compounds produced in vivo by free radical-catalyzed peroxidation of arachidonoyl-containing lipids. 8-iso PGA2 is produced from peroxidation of arachidonic acid esterified in phospholipids(1). 8-iso PGA2 is the dehydration product of 8-iso PGE2, which is a potent renal vasoconstrictor(2). Evidence for the in vivo production of 8-iso PGA2 has been shown in rat liver under conditions of oxidative stress(3). There are no published studies of the pharmacological properties of 8-iso PGA2.
8-iso Prostaglandin A2 (CAS 474391-66-7) References
1 Morrow, J.D., Minton, T.A., Mukundan, C.R., et al. Free radical-induced generation of isoprostanes in vivo. Evidence for the formation of D-ring and E-ring isoprostanes. J Biol Chem 269 4317-4326 (1994). 2 Longmire, A.W., Roberts, L.J., Morrow, J.D. AOrdering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
8-iso Prostaglandin A2, 1 mg | sc-221135 | 1 mg | $180.00 | |||
8-iso Prostaglandin A2, 5 mg | sc-221135A | 5 mg | $900.00 |