Molecular structure of 8-iso Misoprostol, CAS Number: 1256643-55-6
8-iso Misoprostol (CAS 1256643-55-6)
Alternate Names:
methyl7-[3-hydroxy-2-[(E)-4-hydroxy-4-methyloct-1-enyl]-5-oxocyclopentyl] heptanoate
Application:
8-iso Misoprostol is one of several impurities which are possible in the production of bulk commercial preparations of misoprostol.
CAS Number:
1256643-55-6
Molecular Weight:
382.5
Molecular Formula:
C22H38O5
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
Misoprostol is a widely sold analog of prostaglandin E1 (PGE1) that has potent but relatively non-selective agonist activity with respect to the prostanoid EP receptor subgroup(1). Misoprostol has been used therapeutically for many years in humans for treatment of gastric ulcer disease under the Searle tradename Cytotec(2). 8-iso Misoprostol is one of several impurities which are possible in the production of bulk commercial preparations of misoprostol. It is also somewhat difficult to distinguish from other impurities such as 11β-misoprostol(3). The pharmacology and EP receptor binding affinity for 8-iso misoprostol has not been published.
8-iso Misoprostol (CAS 1256643-55-6) References
1 Abramovitz, M., Adam, M., Boie, Y., et al. The utilization of recombinant prostanoid receptors to determine the affinities and selectivities of prostaglandins and related analogs. Biochim Biophys Acta 1483 285-293 (2000). 2 Collins, P.W. Misoprostol: Discovery, development, and clinical applications. Medicinal Research Reviews 10 149-172 (1990). 3 Iyer, R.R. Personal Communication. (2002).Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
8-iso Misoprostol, 1 mg | sc-223751 | 1 mg | $130.00 | |||
8-iso Misoprostol, 5 mg | sc-223751A | 5 mg | $592.00 |