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8-Hydroxy Guanosine-13C,15N2 serves as a research tool in the field of molecular biology and biochemistry, particularly in the study of oxidative DNA damage. This compound is an isotopically labeled analog of 8-hydroxyguanosine, a modified nucleoside that results from the oxidative modification of guanine in RNA and DNA. The incorporation of the stable isotopes carbon-13 and nitrogen-15 enables precise quantification and tracking of 8-hydroxyguanosine within cells and tissues using advanced analytical techniques like mass spectrometry. It is instrumental in investigating the mechanisms of oxidative stress at the molecular level and its implications in various biological processes, including aging and carcinogenesis. Additionally, 8-Hydroxy Guanosine-13C,15N2 is used to explore the efficiency of DNA repair mechanisms in recognizing and correcting oxidative lesions, contributing to a broader understanding of genomic maintenance and stability.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
8-Hydroxy Guanosine-13C,15N2, 0.5 mg | sc-495597 | 0.5 mg | $871.00 | |||
8-Hydroxy Guanosine-13C,15N2, 5 mg | sc-495597A | 5 mg | $6533.00 |