Molecular structure of 8-DY547-cGMP
8-DY547-cGMP
Application:
8-DY547-cGMP is a fluorescently-labeled cyclic nucleotide that′s used to study CNGA2 channel activation
Molecular Weight:
1069.08
Molecular Formula:
C42H55N8O14PS3•2Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Through activation by the binding of cyclic nucleotides, cyclic nucleotide-gated (CNG) ion channels mediate sensory signal transduction in photoreceptors and olfactory cells. 8-DY547-cGMP is a fluorescently-labeled cyclic nucleotide that′s used to study CNGA2 channel activation. 8-DY547-cGMP and cGMP open the channel with equal efficiency and the control of channel activity is rapid and reversible. The difference in fluorescence (ΔF) can be determined by using DY647(1).
8-DY547-cGMP References
- Relating ligand binding to activation gating in CNGA2 channels. | Biskup, C., et al. 2007. Nature. 446: 440-3. PMID: 17322905
- Adding new dimensions to laser-scanning fluorescence microscopy. | De, AK. and Goswami, D. 2009. J Microsc. 233: 320-5. PMID: 19220698
- Apoptotic Body-Mediated Intracellular Delivery Strategy for Enhanced STING Activation and Improved Tumor Immunogenicity. | Bao, P., et al. 2022. Nano Lett. 22: 2217-2227. PMID: 35254071
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
8-DY547-cGMP, 50 µg | sc-221129 | 50 µg | $160.00 | |||
8-DY547-cGMP, 100 µg | sc-221129A | 100 µg | $304.00 |