8,9-EE-14(Z)-E

8,9-EE-14(Z)-E, identified by its CAS number when available, is a chemically intriguing epoxyeicosatrienoic acid (EET) derivative, recognized for its role in the modulation of biological processes through its interaction with cellular systems. This compound is characterized by an epoxide group at the 8,9 positions and a cis double bond at the 14th position, distinguishing it from other EETs in terms of its structural and functional properties. In research contexts, this molecule has been utilized to explore its impact on intracellular signaling pathways, particularly those involving the regulation of ion channels, modulation of protein kinases, and alteration of gene expression. These interactions are crucial for understanding how cells perceive and respond to changes in their environment. The specific actions of 8,9-EE-14(Z)-E include the regulation of calcium flux within cells and the potential modulation of inflammatory signaling pathways, providing critical insights into the cell′s ability to adapt to and manage physiological stresses. Studies focusing on this compound often investigate its role in cellular mechanisms that control vascular functions and inflammatory responses, aiming to delineate the complex web of signaling pathways influenced by lipid-derived molecules in various biological systems.