Molecular structure of 7Z,10Z,13Z,16Z,19Z-Docosapentaenoic acid, CAS Number: 24880-45-3
7Z,10Z,13Z,16Z,19Z-Docosapentaenoic acid (CAS 24880-45-3)
Alternate Names:
Docosapentaenoic acid
Application:
7Z,10Z,13Z,16Z,19Z-Docosapentaenoic acid is a fatty acid shown to inhibit platelet aggregation
CAS Number:
24880-45-3
Purity:
≥98%
Molecular Weight:
330.50
Molecular Formula:
C22H34O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Docosa-7Z,10Z,13Z,16Z,19Z-pentaenoic Acid (22:5, n-3), also known as DPA, is a fatty acid found in fish oils that potently inhibits platelet aggregation. DPA has been reported to block the cyclooxygenase pathway and stimulate the lipoxygenase pathway, which results in effective platelet aggregation inhibition. Peripheral blood mononuclear cell research demonstrates that DPA diminishes cyclooxygenase-2 levels intracellularly and inhibits pro-inflammatory prostaglandin E2 production. Studies indicate that the compound plays an important role in the cubic membrane formation of mitochondria found in amoeba Chaos.
7Z,10Z,13Z,16Z,19Z-Docosapentaenoic acid (CAS 24880-45-3) References
- Involvement of lipoxygenase pathway in docosapentaenoic acid-induced inhibition of platelet aggregation. | Akiba, S., et al. 2000. Biol Pharm Bull. 23: 1293-7. PMID: 11085354
- Fish oil-derived fatty acids, docosahexaenoic acid and docosapentaenoic acid, and the risk of acute coronary events: the Kuopio ischaemic heart disease risk factor study. | Rissanen, T., et al. 2000. Circulation. 102: 2677-9. PMID: 11094031
- Chemical C2-elongation of polyunsaturated fatty acids. | Kuklev, DV. and Smith, WL. 2006. Chem Phys Lipids. 144: 172-7. PMID: 17049508
- Docosapentaenoic acid (DPA) is a critical determinant of cubic membrane formation in amoeba Chaos mitochondria. | Deng, Y., et al. 2009. FASEB J. 23: 2866-71. PMID: 19406841
- Docosahexaenoic acid (DHA) and docosapentaenoic acid (DPAn-6) algal oils reduce inflammatory mediators in human peripheral mononuclear cells in vitro and paw edema in vivo. | Nauroth, JM., et al. 2010. Lipids. 45: 375-84. PMID: 20364438
- Cyclooxygenase-2 generates anti-inflammatory mediators from omega-3 fatty acids. | Groeger, AL., et al. 2010. Nat Chem Biol. 6: 433-41. PMID: 20436486
- Docosapentaenoic acid (22:5n-3): a review of its biological effects. | Kaur, G., et al. 2011. Prog Lipid Res. 50: 28-34. PMID: 20655949
- Specialized pro-resolving lipid mediators in the inflammatory response: An update. | Bannenberg, G. and Serhan, CN. 2010. Biochim Biophys Acta. 1801: 1260-73. PMID: 20708099
- Novel n-3 immunoresolvents: structures and actions. | Dalli, J., et al. 2013. Sci Rep. 3: 1940. PMID: 23736886
- Total synthesis of the lipid mediator PD1n-3 DPA: configurational assignments and anti-inflammatory and pro-resolving actions. | Aursnes, M., et al. 2014. J Nat Prod. 77: 910-6. PMID: 24576195
- Metabolomic study of the intervention effects of Shuihonghuazi Formula, a Traditional Chinese Medicinal formulae, on hepatocellular carcinoma (HCC) rats using performance HPLC/ESI-TOF-MS. | Bao, Y., et al. 2017. J Ethnopharmacol. 198: 468-478. PMID: 28108381
- Metabolomic and Lipidomic Approaches to Evaluate the Effects of Eucommia ulmoides Leaves on Milk Quality and Biochemical Properties. | Teng, Z., et al. 2021. Front Vet Sci. 8: 644967. PMID: 34141731
- Plasma-metabolite-based machine learning is a promising diagnostic approach for esophageal squamous cell carcinoma investigation. | Chen, Z., et al. 2021. J Pharm Anal. 11: 505-514. PMID: 34513127
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Cox.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
7Z,10Z,13Z,16Z,19Z-Docosapentaenoic acid, 1 mg | sc-200786 | 1 mg | $91.00 | |||
7Z,10Z,13Z,16Z,19Z-Docosapentaenoic acid, 10 mg | sc-200786A | 10 mg | $148.00 | |||
7Z,10Z,13Z,16Z,19Z-Docosapentaenoic acid, 50 mg | sc-200786B | 50 mg | $265.00 |