Date published: 2025-12-1

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(7R,10S)-(+)-1-Aza-10-isopropyl-8-oxa-4-thiabicyclo[5.3.0]-2-decanone

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Molecular Weight:
215.31
Molecular Formula:
C10H17NO2S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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This chiral lactam auxiliary has been successfully used in the stereocontrolled synthesis of all carbon quaternary centers. The unique methodology generated by Gleason allows for the creation of antipode of the product using a single isomer of the auxiliary.


(7R,10S)-(+)-1-Aza-10-isopropyl-8-oxa-4-thiabicyclo[5.3.0]-2-decanone References

  1. A practical chiral bicyclic thioglycolate lactam auxiliary for stereoselective quaternary carbon formation.  |  Arpin, A., et al. 2006. Org Lett. 8: 1359-62. PMID: 16562891

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

(7R,10S)-(+)-1-Aza-10-isopropyl-8-oxa-4-thiabicyclo[5.3.0]-2-decanone, 1 g

sc-291657
1 g
$71.00