7β-Hydroxy Cholesterol (CAS 566-27-8)
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7β-Hydroxy Cholesterol (7β-HC), an oxysterol naturally present in humans and other mammals, plays a significant role in cholesterol metabolism. It is generated through the oxidation of cholesterol and serves as a vital intermediate in the synthesis of various oxysterols, including 7-ketocholesterol. Moreover, 7β-Hydroxy Cholesterol acts as a precursor for the production of multiple steroids and bile acids. One of the key mechanisms through which 7β-Hydroxy Cholesterol exerts its effects is by acting as a cholesterol-regulating agent. It achieves this by inhibiting the activity of HMG-CoA reductase, an enzyme responsible for cholesterol synthesis. Moreover, 7β-Hydroxy Cholesterol has been found to modulate the activity of several other enzymes, including cholesterol ester transfer protein, acyl-CoA:cholesterol acyltransferase, and lecithin cholesterol acyltransferase.
7β-Hydroxy Cholesterol (CAS 566-27-8) References
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
7β-Hydroxy Cholesterol, 1 mg | sc-210655 | 1 mg | $245.00 |