7(Z),11(Z)-Pentacosadiene (CAS 127599-39-7)
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Unsaturated, long-chain hydrocarbons are found on the cuticles of insects and can act as pheromones. In mature Drosophila melanogaster, certain cuticular hydrocarbons are sexually dimorphic: males synthesize 23- and 25-C monoenes and females produce 27- and 29-C dienes. Each of these lipids plays specific roles in regulating male sexual behavior, with dienes stimulating courtship. 7(Z),11(Z)-Pentacosadiene is a 25-C hydrocarbon that is found in low abundance on cuticles of mature Drosophila females. Depletion of a female-specific elongase (eloF), which leads to an increase in 7(Z),11(Z)-pentacosadiene along with a parallel decrease in 7,11-nonacosadiene, significantly reduces copulation in Drosophila. This raises the possibility that 7(Z),11(Z)-pentacosadiene may act as an anti-aphrodisiac.
7(Z),11(Z)-Pentacosadiene (CAS 127599-39-7) References
1 Ferveur, J., Sureau, G. Simultaneous influences on male courtship of stimulatory and inhibitory pheromones produced by live sex-mosaic Drosophila melanogaster. Proceedings Biological Sciences 263(1373) 967-973 (1996). 2 Siwicki, K.K., Riccio, P., Ladewski, L., et al. The role of cuticular pheromones in courtship conditioning of Drosophila males. Learning & Memory 12 636-645 (2005). 3 Chertemps, T., Duportets, L., Labuer, C., et al. A female-biased expressed elongase involved in long-chain hydrocarbon biosynthesis and courtship behavior in Drosophila melanogaster. Proc Natl Acad Sci USA 104(11) 4273-4278 (2007).Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
7(Z),11(Z)-Pentacosadiene, 1 mg | sc-291656 | 1 mg | $63.00 | |||
7(Z),11(Z)-Pentacosadiene, 5 mg | sc-291656A | 5 mg | $284.00 |