Date published: 2026-5-1

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7-Methoxyindole (CAS 3189-22-8)

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Alternate Names:
NSC 100739
CAS Number:
3189-22-8
Molecular Weight:
147.17
Molecular Formula:
C9H9NO
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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7-methoxyindole, is indole derivative, a small molecule that can be synthesized in the laboratory, has found utility in diverse scientific fields for research purposes. Scientists have delved into the potential roles of 7-methoxyindole in various scientific research applications. It has served as a model compound to investigate the impacts of indole derivatives. Furthermore, it has been instrumental in studying the effects of indole-3-carboxaldehyde on the synthesis of indole derivatives. Additionally, 7-methoxyindole has shed light on the influence of indole derivatives on enzyme activity, notably the cytochrome P450 enzymes. While the precise mechanism of action of 7-methoxyindole remains elusive, it is known to interact with cytochrome P450 enzymes.


7-Methoxyindole (CAS 3189-22-8) References

  1. Microbial transformation of aspidospermine.  |  Lin, SK., et al. 1975. J Pharm Sci. 64: 2021-2. PMID: 1206502
  2. Utilization of indole analogs by carrot and tobacco cell tryptophan synthase in vivo and in vitro.  |  Widholm, JM. 1981. Plant Physiol. 67: 1101-4. PMID: 16661817
  3. Direct palladium-catalyzed C-3 arylation of free (NH)-indoles with aryl bromides under ligandless conditions.  |  Bellina, F., et al. 2008. J Org Chem. 73: 5529-35. PMID: 18543968
  4. Design, synthesis, and biological evaluation of aminoalkylindole derivatives as cannabinoid receptor ligands with potential for treatment of alcohol abuse.  |  Vasiljevik, T., et al. 2013. J Med Chem. 56: 4537-50. PMID: 23631463
  5. Biomimetic Enantioselective Total Synthesis of (-)-Mycoleptodiscin A.  |  Dethe, DH., et al. 2016. Org Lett. 18: 6392-6395. PMID: 27978704
  6. Methylindoles and Methoxyindoles are Agonists and Antagonists of Human Aryl Hydrocarbon Receptor.  |  Stepankova, M., et al. 2018. Mol Pharmacol. 93: 631-644. PMID: 29626056
  7. Design, Synthesis and Evaluation of New Indolylpyrimidylpiperazines for Gastrointestinal Cancer Therapy.  |  Tan, A., et al. 2019. Molecules. 24: PMID: 31614517
  8. Antibiofilm and Antivirulence Properties of Indoles Against Serratia marcescens.  |  Sethupathy, S., et al. 2020. Front Microbiol. 11: 584812. PMID: 33193228
  9. The Anticancer Agent 3,3'-Diindolylmethane Inhibits Multispecies Biofilm Formation by Acne-Causing Bacteria and Candida albicans.  |  Kim, YG., et al. 2022. Microbiol Spectr. 10: e0205621. PMID: 35107361
  10. Free energy perturbation (FEP)-guided scaffold hopping.  |  Wu, D., et al. 2022. Acta Pharm Sin B. 12: 1351-1362. PMID: 35530128
  11. Characterization of marine-derived halogenated indoles as ligands of the aryl hydrocarbon receptor.  |  King, J., et al. 2022. Toxicol Rep. 9: 1198-1203. PMID: 36518459
  12. The Impact of Indoles Activating the Aryl Hydrocarbon Receptor on Androgen Receptor Activity in the 22Rv1 Prostate Cancer Cell Line.  |  Zgarbová, E. and Vrzal, R. 2022. Int J Mol Sci. 24: PMID: 36613955
  13. Molecular orbital calculations of magnetic circular dichroism spectra: a benzene-indole sequence.  |  Miles, DW. and Eyring, H. 1973. Proc Natl Acad Sci U S A. 70: 3754-8. PMID: 4521200

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

7-Methoxyindole, 1 g

sc-254908
1 g
$110.00