Molecular structure of 7-Keto-3α,12-α-dihydroxycholanic Acid, CAS Number: 911-40-0
7-Keto-3α,12-α-dihydroxycholanic Acid (CAS 911-40-0)
Alternate Names:
(3α,5β,12α)-3,12-Dihydroxy-7-oxo-cholan-24-oic Acid; 3α,12α-Dihydroxy-7-keto-5β-cholanic Acid; 7-Oxodeoxycholic Acid; 5β-Cholanic Acid-3α,12α-diol-7-one
Application:
7-Keto-3α,12-α-dihydroxycholanic Acid is A steroid acid
CAS Number:
911-40-0
Molecular Weight:
406.56
Molecular Formula:
C24H38O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
7-Ketodeoxycholic acid is a bile acid. Bile acids are steroid acids found predominantly in bile of mammals. The distinction between different bile acids is minute, depends only on presence or absence of hydroxyl groups on positions 3, 7, and 12. Bile acids are physiological detergents that facilitate excretion, absorption, and transport of fats and sterols in the intestine and liver. Bile acids are also steroidal amphipathic molecules derived from the catabolism of cholesterol.
7-Keto-3α,12-α-dihydroxycholanic Acid (CAS 911-40-0) References
- Identification of short side chain bile acids in urine of patients with cerebrotendinous xanthomatosis. | Kuramoto, T., et al. 1990. J Lipid Res. 31: 1895-902. PMID: 2079611
- Identification and Distribution of Sterols, Bile Acids, and Acylcarnitines by LC-MS/MS in Humans, Mice, and Pigs-A Qualitative Analysis. | Babu, AF., et al. 2022. Metabolites. 12: PMID: 35050171
- Bile acid profiles in bile, urine, and feces of a patient with cerebrotendinous xanthomatosis. | Kihira, K., et al. 1986. Steroids. 48: 109-19. PMID: 3660436
- Evaluation of the 3 alpha-hydroxysteroid dehydrogenase assay for ursodeoxycholic acid, and 7 oxo- and 12 oxo- bile acids. | Haeffner, LJ., et al. 1980. J Lipid Res. 21: 477-80. PMID: 6929859
- The metabolism of primary, 7-oxo, and 7 beta-hydroxy bile acids by Clostridium absonum. | Sutherland, JD. and Macdonald, IA. 1982. J Lipid Res. 23: 726-32. PMID: 7119570
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
7-Keto-3α,12-α-dihydroxycholanic Acid, 50 mg | sc-207176 | 50 mg | $464.00 |