Date published: 2025-9-18

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7-Iodoacetamidocoumarin-4-carboxylic Acid (CAS 284679-24-9)

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Alternate Names:
I-Cca
Application:
7-Iodoacetamidocoumarin-4-carboxylic Acid is a thio-reactive fluorescent probe
CAS Number:
284679-24-9
Molecular Weight:
373.10
Molecular Formula:
C12H8INO5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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7-Iodoacetamidocoumarin-4-carboxylic Acid is a water-soluble thio-reactive fluorescent probe. 7-Iodoacetamidocoumarin-4-carboxylic acid (7-IAC) is an innovative compound recently developed for diverse scientific applications. It is derived from coumarin, a group of aromatic compounds found in plants known for their broad range of biological activities. 7-IAC is a highly stable fluorescent compound that finds extensive utility in chemical, biochemical, and physiological research.


7-Iodoacetamidocoumarin-4-carboxylic Acid (CAS 284679-24-9) References

  1. Design consideration and probes for fluorescence resonance energy transfer studies.  |  Sinev, M., et al. 2000. Bioconjug Chem. 11: 352-62. PMID: 10821651
  2. Formation of the hydrophobic core of ribonuclease A through sequential coordinated conformational transitions.  |  Navon, A., et al. 2002. Biochemistry. 41: 14225-31. PMID: 12450386
  3. Early closure of a long loop in the refolding of adenylate kinase: a possible key role of non-local interactions in the initial folding steps.  |  Orevi, T., et al. 2009. J Mol Biol. 385: 1230-42. PMID: 19013178
  4. Time-resolved FRET detection of subtle temperature-induced conformational biases in ensembles of α-synuclein molecules.  |  Grupi, A. and Haas, E. 2011. J Mol Biol. 411: 234-47. PMID: 21570984
  5. Kinetics of fast changing intramolecular distance distributions obtained by combined analysis of FRET efficiency kinetics and time-resolved FRET equilibrium measurements.  |  Lerner, E., et al. 2014. Biophys J. 106: 667-76. PMID: 24507607

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

7-Iodoacetamidocoumarin-4-carboxylic Acid, 10 mg

sc-217455
10 mg
$337.00