Date published: 2025-10-17

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7-Hydroxyflavone (CAS 6665-86-7)

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Alternate Names:
7-Hydroxy-2-phenyl-4-benzopyrone
Application:
7-Hydroxyflavone is involved in synthesis of fully phosphorylated flavones
CAS Number:
6665-86-7
Purity:
≥98%
Molecular Weight:
238.24
Molecular Formula:
C15H10O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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7-Hydroxyflavone is extensively used in research focused on its bioactive properties and interactions with other organic molecules. As a flavone, it is useful in the study of molecular signaling pathways and receptor-binding activities. 7-Hydroxyflavone is utilized in chemical synthesis to explore its potential as a dye and to investigate its photophysical properties, which are relevant for developing optical sensors and other photonic devices. Its role in catalysis is examined, particularly in reactions that involve the transfer of hydroxyl groups.


7-Hydroxyflavone (CAS 6665-86-7) References

  1. Protein engineering on biphenyl dioxygenase for conferring activity to convert 7-hydroxyflavone and 5,7-dihydroxyflavone (chrysin).  |  Kagami, O., et al. 2008. J Biosci Bioeng. 106: 121-7. PMID: 18804053
  2. Metabolism and pharmacokinetics of 3,3',4',7-tetrahydroxyflavone (fisetin), 5-hydroxyflavone, and 7-hydroxyflavone and antihemolysis effects of fisetin and its serum metabolites.  |  Shia, CS., et al. 2009. J Agric Food Chem. 57: 83-9. PMID: 19090755
  3. Simultaneous quantitation of 5- and 7-hydroxyflavone antioxidants and their binding constants with BSA using dual chiral capillary electrophoresis (dCCE) and HPLC with fluorescent detection.  |  Abo Markeb, A. and Abo El-Maali, N. 2014. Talanta. 119: 417-24. PMID: 24401434
  4. Inhibition of Enterovirus 71 replication by 7-hydroxyflavone and diisopropyl-flavon7-yl Phosphate.  |  Wang, J., et al. 2014. PLoS One. 9: e92565. PMID: 24664133
  5. 7-hydroxyflavone revisited: spectral, acid-base properties, and interplay of the protolytic forms in the ground and excited states.  |  Serdiuk, IE., et al. 2014. J Phys Chem A. 118: 3068-80. PMID: 24689737
  6. Host-guest interaction of 3-hydroxyflavone and 7-hydroxyflavone with cucurbit [7]uril: A spectroscopic and calorimetric approach.  |  Ahmed, SA., et al. 2017. J Photochem Photobiol B. 168: 132-141. PMID: 28214719
  7. Inhibition of pro-inflammatory mediators in RAW264.7 cells by 7-hydroxyflavone and 7,8-dihydroxyflavone.  |  Jin, Z., et al. 2017. J Pharm Pharmacol. 69: 865-874. PMID: 28295316
  8. Differential roles of 3-Hydroxyflavone and 7-Hydroxyflavone against nicotine-induced oxidative stress in rat renal proximal tubule cells.  |  Sengupta, B., et al. 2017. PLoS One. 12: e0179777. PMID: 28640852
  9. Exploring the non-covalent binding behaviours of 7-hydroxyflavone and 3-hydroxyflavone with hen egg white lysozyme: Multi-spectroscopic and molecular docking perspectives.  |  Das, S., et al. 2018. J Photochem Photobiol B. 180: 25-38. PMID: 29413699
  10. Electron spectroscopies of 3-hydroxyflavone and 7-hydroxyflavone in MCM-41 silica nanoparticles and in acetonitrile solutions. Experimental data and DFT/TD-DFT calculations.  |  Landström, A., et al. 2021. Data Brief. 34: 106630. PMID: 33409341
  11. The 7-Hydroxyflavone attenuates chemotherapy-induced neuropathic pain by targeting inflammatory pathway.  |  Ullah, R., et al. 2022. Int Immunopharmacol. 107: 108674. PMID: 35276461
  12. 7-Hydroxyflavone Alleviates Myocardial Ischemia/Reperfusion Injury in Rats by Regulating Inflammation.  |  Zhang, Q., et al. 2022. Molecules. 27: PMID: 36080137
  13. Single -and Multi-Walled Carbon Nanotubes as Nanocarriers for the Delivery of 7-Hydroxyflavone.  |  Espíndola, C., et al. 2022. Pharmaceutics. 14: PMID: 36559299

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

7-Hydroxyflavone, 1 g

sc-257010
1 g
$33.00

7-Hydroxyflavone, 5 g

sc-257010A
5 g
$92.00

7-Hydroxyflavone, 25 g

sc-257010B
25 g
$306.00

7-Hydroxyflavone, 100 g

sc-257010C
100 g
$867.00