Date published: 2026-4-24

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7-Hydroxy Risperidone (CAS 147663-04-5)

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Application:
7-Hydroxy Risperidone is a metabolite of Risperidone
CAS Number:
147663-04-5
Molecular Weight:
426.48
Molecular Formula:
C23H27FN4O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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7-Hydroxy Risperidone is a metabolite of Risperidone. It functions as an active metabolite that interacts with dopamine and serotonin receptors in the brain. This interaction modulates neurotransmitter activity, leading to changes in neuronal signaling and neurotransmission. 7-Hydroxy Risperidone acts as an antagonist at dopamine D2 and serotonin 5-HT2 receptors, inhibiting their activity. This modulation of receptor function can impact various physiological processes, providing insight into the molecular mechanisms underlying certain neurological conditions. 7-Hydroxy Risperidone′s mechanism of action involves influencing the balance of neurotransmitters in the brain, which may have implications for understanding the pathophysiology of certain psychiatric disorders. Its role in modulating receptor activity contributes to the exploration of neurobiological processes and the development of potential experimental models for studying neurological conditions.


7-Hydroxy Risperidone (CAS 147663-04-5) References

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  2. An evaluation of risperidone drug interactions.  |  DeVane, CL. and Nemeroff, CB. 2001. J Clin Psychopharmacol. 21: 408-16. PMID: 11476125
  3. Determination of risperidone and 9-hydroxyrisperidone in plasma, urine and animal tissues by high-performance liquid chromatography.  |  Woestenborghs, R., et al. 1992. J Chromatogr. 583: 223-30. PMID: 1282517
  4. Pharmacogenomics and the future of toxicology testing.  |  Agrawal, YP. and Rennert, H. 2012. Clin Lab Med. 32: 509-23. PMID: 22939305
  5. Investigating the cubosomal ability for transnasal brain targeting: In vitro optimization, ex vivo permeation and in vivo biodistribution.  |  Abdelrahman, FE., et al. 2015. Int J Pharm. 490: 281-91. PMID: 26026251
  6. Genetic Polymorphisms Associated With the Pharmacokinetics, Pharmacodynamics and Adverse Effects of Olanzapine, Aripiprazole and Risperidone.  |  Soria-Chacartegui, P., et al. 2021. Front Pharmacol. 12: 711940. PMID: 34335273

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

7-Hydroxy Risperidone, 2.5 mg

sc-210619
2.5 mg
$555.00