Molecular structure of 7-Hydroxy-PIPAT maleate, CAS Number: 159559-71-4
7-Hydroxy-PIPAT maleate (CAS 159559-71-4)
Application:
7-Hydroxy-PIPAT maleate is a ligand with high selectivity for the D3DR receptor
CAS Number:
159559-71-4
Purity:
98%
Molecular Weight:
487.33
Molecular Formula:
C16H22INO•C4H4O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
7-Hydroxy-PIPAT maleate is a ligand that has been shown to have high selectivity and affinity for the D3 receptor.
7-Hydroxy-PIPAT maleate (CAS 159559-71-4) References
- Dopaminergic modulation on respiratory rhythm in rat brainstem-spinal cord preparation. | Fujii, M., et al. 2004. Neurosci Res. 50: 355-9. PMID: 15488298
- Dopamine desynchronizes the pace-making neuronal activity of rat respiratory rhythm generation. | Fujii, M., et al. 2006. Eur J Neurosci. 23: 1015-27. PMID: 16519666
- Evidence for a dopamine intrinsic direct role in the regulation of the ovary reproductive function: in vitro study on rabbit corpora lutea. | Parillo, F., et al. 2014. PLoS One. 9: e104797. PMID: 25148384
- Neuroregeneration in Parkinson's Disease: From Proteins to Small Molecules. | Sidorova, YA., et al. 2019. Curr Neuropharmacol. 17: 268-287. PMID: 30182859
- A Potential Strategy for Treatment of Neurodegenerative Disorders by Regulation of Adult Hippocampal Neurogenesis in Human Brain. | Xie, WS., et al. 2022. Curr Med Chem. 29: 5315-5347. PMID: 35579169
- Synthesis of (R,S)-2'-trans-7-hydroxy-2-[N-n-propyl-N-(3'-iodo-2'- propenyl)-amino]tetralin (trans-7-OH-PIPAT): a new D3 dopamine receptor ligand. | Foulon, C., et al. 1993. J Med Chem. 36: 1499-500. PMID: 8098771
- Synthesis and optical resolution of (R)- and (S)-trans-7-Hydroxy-2-[N-propyl-N-(3'-iodo-2'-propenyl)amino]tetralin: a new D3 dopamine receptor ligand. | Chumpradit, S., et al. 1993. J Med Chem. 36: 4308-12. PMID: 8277513
- In vitro binding of a novel dopamine D3 receptor ligand: [125I]trans-7-OH-PIPAT-A. | Kung, MP., et al. 1993. Eur J Pharmacol. 235: 165-6. PMID: 8519278
- Serotonin 5-HT2B receptor antagonism is fundamental for protecting PC12 cells exposed to hydrogen peroxide[J]. | Takayanagi T, Nagasaki H, Kodani Y. 2015,. Fujita medical journal,. 1(1):: 1-5.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
7-Hydroxy-PIPAT maleate, 5 mg | sc-361088 | 5 mg | $197.00 | |||
7-Hydroxy-PIPAT maleate, 50 mg | sc-361088A | 50 mg | $670.00 |